alfaxalone

Known as: alphaxalone, alfaxolone, delta(16)-alfaxalone 
 
National Institutes of Health

Papers overview

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2012
2012
OBJECTIVE To compare the anaesthetic and cardiopulmonary effects of alfaxalone with propofol when used for total intravenous… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE To determine the cardiorespiratory and anesthetic effects of 2, 6, and 20 mg kg(-1) IV alfaxalone in hydroxypropyl beta… (More)
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2008
2008
OBJECTIVE To determine the cardiorespiratory and anesthetic effects of 0, 5, 15, and 50 mg kg(-1) intravenous (IV) alfaxalone in… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To determine the pharmacokinetic parameters of alfaxalone in dogs after the intravenous (IV) administration of clinical… (More)
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Highly Cited
2000
Highly Cited
2000
Purpose. The present study investigates fast negative feedback actions of corticosterone (corticosteroid type I/type II receptor… (More)
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Highly Cited
1998
Highly Cited
1998
Both volatile and intravenous general anesthetics allosterically enhance gamma-aminobutyric acid (GABA)-evoked chloride currents… (More)
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Highly Cited
1997
Highly Cited
1997
Anesthetic drugs are known to interact with GABAA receptors, both to potentiate the effects of low concentrations of GABA and to… (More)
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Highly Cited
1993
Highly Cited
1993
γ-AMlNOBUTYRlC acid (GABA), a major inhibitory neurotransmitter in the mammalian nervous system, is known to operate bicuculline… (More)
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Highly Cited
1993
Highly Cited
1993
Progesterone (4-pregnen-3-20-dione) initiates the acrosome reaction (AR) of human sperm in vitro. Anesthetic progestins (e.g… (More)
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Highly Cited
1988
Highly Cited
1988
This report presents evidence that colorectal distension is a reproducible, reliable, valid, noxious visceral stimulus that can… (More)
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