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alfaxalone

Known as: alphaxalone, alfaxolone, delta(16)-alfaxalone 
National Institutes of Health

Related topics

Related topics

6 relations
ALFAXALONE 10 mg in 1 mL INTRAVENOUS INJECTION, SOLUTION [ALFAXAN]Ketamine

Broader (2)

AnestheticsPregnanediones

Narrower (2)

alphaxalone, (3alpha)-isomeralphaxalone, (3alpha,5beta)-isomer

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain
Highly Cited
2003
Highly Cited
2003
Comparison of Effect of Ethanol onN-Methyl-d-aspartate- and GABA-Gated Currents from Acutely Dissociated Neurons: Absence of Regional Differences in Sensitivity to Ethanol
In vivo, ethanol alters the effect ofN-methyl-d-aspartate (NMDA) and GABA in some brain regions but is without effect in others… 
Highly Cited
2000
Highly Cited
2000
Antinociceptive properties of neurosteroids II. Experiments with Saffan® and its components alphaxalone and alphadolone to reveal separation of anaesthetic and antinociceptive effects and the…
Highly Cited
1996
Highly Cited
1996
Preemptive Analgesic Effects of Steroid Anesthesia with Alphaxalone in the Rat Formalin Test: Evidence for Differential GABA‐A Receptor Modulation in Persistent Nociception
Background The role of preemptive treatment with volatile and intravenous anesthetics has been examined in previous studies using… 
1991
1991
Effects of inhalation and intravenous anaesthetic agents on presser response to NG-nitro-L-arginine
Highly Cited
1990
Highly Cited
1990
The General Anesthetic Propofol Enhances the Function of γ‐Aminobutyric Acid‐Coupled Chloride Channel in the Rat Cerebral Cortex
Abstract: The effect of the general anesthetic propofol on t‐[35S]butylbicyclophosphorothionate ([35S]TBPS) binding to unwashed… 
Highly Cited
1985
Highly Cited
1985
Action of phospholipase A2 on bilayers. Effect of inhibitors.
Highly Cited
1981
Highly Cited
1981
Gonadotropin-releasing hormone surge: possible modulation through postsynaptic alpha-adrenoreceptors and two pharmacologically distinct dopamine receptors.
We have studied modulation of the release of gonadotropin-releasing hormone (GnRH) by central monoaminergic neurons. The test… 
Highly Cited
1980
Highly Cited
1980
Gonadotropin-releasing hormone (GnRH) in pituitary stalk blood from proestrous rats: effects of anesthetics and relationship between stored and released GnRH and luteinizing hormone.
We have studied the effects of various anesthetics on the spontaneous release of gonadotropin-releasing hormone (GnRH) into… 
Highly Cited
1977
Highly Cited
1977
Pharmacokinetics of Intravenous Anaesthetics: Implications for Clinical Use
SummaryIntravenous anaesthetics comprise a variety of drugs that differ in chemical structure but share a suitable combination of… 
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