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aldophosphamide

Known as: Cyp-mustard, cyclophosphamide-mustard 
National Institutes of Health

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Phosphoramide Mustards

Papers overview

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1995
1995
Measurement of 4-hydroxycyclophosphamide in serum by reversed-phase high-performance liquid chromatography.
1994
1994
Detoxification of cyclophosphamide by human aldehyde dehydrogenase isozymes.
Highly Cited
1993
Highly Cited
1993
Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
1990
1990
Biotransformation of mafosfamide in P388 mice leukemia cells: intracellular 31P-NMR studies.
1989
1989
Proton-mediated liberation of aldophosphamide from a nontoxic prodrug: a strategy for tumor-selective activation of cytocidal drugs.
Based on the findings that the pH in malignant tumors can be preferentially decreased by stimulation of their aerobic glycolysis… 
1987
1987
Effects of aldehyde dehydrogenase inhibitors on the ex vivo sensitivity of murine late spleen colony-forming cells (day-12 CFU-S) and hematopoietic repopulating cells to mafosfamide (ASTA Z 7557).
1986
1986
Synthesis and antitumor activity of cyclophosphamide analogues. 4. Preparation, kinetic studies, and anticancer screening of "phenylketophosphamide" and similar compounds related to the…
Phenyl ketone phosphorodiamidates [C6H5C(O)CH2CH2OP(O)NHR1NR2R3] were synthesized in conjunction with an ongoing investigation… 
1986
1986
The enzymatic basis of cyclophosphamide specificity.
1984
1984
In situ preparation and fate of cis-4-hydroxycyclophosphamide and aldophosphamide: 1H and 31P NMR evidence for equilibration of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and its…
cis-4-Hydroxycyclophosphamide (2) and aldophosphamide (4) were generated in aqueous phosphate or cacodylate buffer by dimethyl… 
1974
1974
Isolation and identification of a stabilized derivative of aldophosphamide, a major metabolite of cyclophosphamide.
Aldophosphamide semicarbazone was synthesized from 4-hydroxycyclophosphamide and characterized by infrared and proton magnetic… 
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