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alanosine

Known as: L-Alanosine, L-2-amino-3-(N-nitroso)hydroxylaminopropionic acid, 3-(Hydroxynitrosoamino)-L-alanine 
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

AlanineAntibiotics, AntineoplasticChelating Agents

Narrower (2)

NSC 153,353SDX 102
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1985
1985
L-alanosine: a noncooperative substrate for Escherichia coli aspartate transcarbamylase.
L-Alanosine, an antibiotic produced by Streptomyces alanosinicus, can be used by Escherichia coli aspartate transcarbamylase as a… 
1984
1984
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
Toxic guanine depletion was shown previously to result in a dramatic reduction of DNA synthesis, while toxic adenine depletion… 
1981
1981
Uptake of 14C-labeled dicarboxylic amino acids in hepatocytes and hepatoma cells.
In previous studies, we observed decreased uptake of 14C-labeled L-aspartate and L-glutamate in s.c. transplants of several… 
1978
1978
Inhibition of mouse molar tooth germ morphogenesis in organ culture by alanosine.
Alanosine (2-amino-3-[hydroxynitrosoamino] propionic acid) an extracellular antitumor product of Streptomyces inhibits the in… 
1977
1977
Pharmacologic disposition of DL-alanosine in mice, rats, dogs, and monkeys.
The pharmacologic disposition of DL-alanosine was studied in mice, rats, dogs, and monkeys. The major portion of the parenterally… 
1973
1973
Microbiological Assay for Estimating Concentrations of dl-Alanosine in Mouse Tissue
A sensitive, precise microbiological assay was developed for the determination of tissue distribution of dl-alanosine, a new… 
1973
1973
Improved synthesis of DL-alanosine.
Highly Cited
1971
Highly Cited
1971
A new reduced human-mouse somatic cell hybrid containing the human gene for adenine phosphoribosyltransferase.
A system that selects for the gene directing synthesis of the enzyme adenine phosphoribosyltransferase (APRT) uses the antibiotic… 
1970
1970
Further investigations on the immunosuppressive effect of alanosine.
1966
1966
Alanosine, a new antiviral and antitumor antibiotic from streptomyces.