Skip to search formSkip to main contentSkip to account menu

alanine-tRNA ligase activity

Known as: alanyl-transfer ribonucleic acid synthetase activity, alanyl-transfer ribonucleate synthase activity, alanine transfer RNA synthetase activity 
Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). [EC:6.1.1.7]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
ABSTRACT Aminoacyl-tRNA synthetases provide the first step in protein synthesis quality control by discriminating cognate from… 
2006
2006
It's not clear what general level of accuracy is required in translating the genetic code. But the protective role of proof… 
2002
2002
Specific aminoacylation by aminoacyl-tRNA synthetases requires accurate recognition of cognate tRNA substrates. In the case of… 
Highly Cited
1998
Highly Cited
1998
An improved quantitative assay for tRNA aminoacylation is presented based on charging of a nicked tRNA followed by separation of… 
1996
1996
G.U wobble pairs are crucial to many examples of RNA-protein recognition. We previously concluded that the G.U wobble pair in the… 
1995
1995
The class-defining active site domain of the 10 class II tRNA synthetases is well conserved and, based on the crystal structure… 
1994
1994
Structural motifs 2 and 3, located in the active site of class II aminoacyl-tRNA synthetases, each contain an invariant arginine… 
1993
1993
Lysine73, located in the adenylate synthesis domain of Escherichia coli alanyl-tRNA synthetase (AlaRS), was previously indicated… 
1962
1962
The existence of life under nonterrestrial conditions has been a subject of extended literary and scientific interest. Astronomy…