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alagebrium

Known as: 3-phenacyl-4,5-dimethylthiazolium chloride, phenyl-4,5-dimethylthiazolium chloride 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

ALT 711

Broader (1)

Thiazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Alagebrium targets the miR-27b/TSP-1 signaling pathway to rescue Nε-carboxymethyl-lysine-induced endothelial dysfunction.
Nε-carboxymethyl-lysine (CML), a major isoform of advanced glycation end products (AGEs), plays a crucial role in the functional… 
2019
2019
Alagebrium and spironolactone ameliorate dietary induced metabolic syndrome in male Wister rats
Accept Date 2019-08-20 Abstract Background: Metabolic syndrome (MS) is associated with chronic hyperglycemia, which leads to… 
2018
2018
Evaluation of N-Hydroxy-, N-Metoxy-, and N-Acetoxybenzoyl-Substituted Derivatives of Thymine and Uracil as New Substances for Prevention and Treatment of Long-Term Complications of Diabetes Mellitus
New uracil and thymine derivatives, N1-,N3- and N1,N3-(RO-benzoyl)-(1H,3H)-pyrimidine- 2,4-diones, were synthesized (RO- is… 
Review
2015
Review
2015
Effect of non-antihypertensive drugs on endothelial function in hypertensive subjects evaluated by flow-mediated vasodilation.
Hypertension (HTN) is a major risk factor for atherosclerosis. Flow-mediated vasodilation (FMD) is an ultrasonic method used to… 
Review
2014
Review
2014
231 Circulation : Heart Failure Topic Review Cardiovascular Effects of 1 Year of Alagebrium and Endurance Exercise Training in Healthy Older Individuals
Lifelong exercise training maintains a youthful compliance of the left ventricle (LV), whereas a year of exercise training… 
2014
2014
AB82. AGE-breaker ALT-711 plus insulin could restore erectile function in streptozocin-induced type 1 diabetic rats
Introduction The interaction between advanced glycation end-products (AGEs) and its receptors for AGEs (RAGEs) elicits oxidative… 
2014
2014
Circulation: Heart Failure Editors’ Picks Most Important Articles in Heart Failure and Exercise
Summary : Lifelong exercise training maintains a youthful compliance of the left ventricle (LV), whereas a year of exercise… 
2014
2014
Effects of Exercise on Left Ventricular Systolic and Diastolic Properties in Patients With Heart Failure and a Preserved Ejection Fraction Versus Heart Failure and a Reduced Ejection Fraction
Lifelong exercise training maintains a youthful compliance of the left ventricle (LV), whereas a year of exercise training… 
2013
2013
Interference of ramipril combined with alagebrium on aorta stiffness in spontaneously hypertensive rats
Objective:To investigate the effect and mechanism of ramipril combined with alagebrium on blood pressure and arteriosclerosis… 
2010
2010
RESEARCH PAPER Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats
Background and purpose: Alagebrium is a breaker of cross-links in advanced glycation endproducts. However, the acute effects of… 
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