aflibercept

Known as: Vascular Endothelial Growth Factor Trap, VEGF Trap R1R2, VEGF Trap 
A protein comprised of segments of the extracellular domains of human vascular endothelial growth factor receptors 1 (VEGFR1) and 2 (VEGFR2) fused to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
PURPOSE To provide 2-year results comparing anti-vascular endothelial growth factor (VEGF) agents for center-involved diabetic… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND The relative efficacy and safety of intravitreous aflibercept, bevacizumab, and ranibizumab in the treatment of… (More)
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Highly Cited
2014
Highly Cited
2014
PURPOSE To determine efficacy and safety of intravitreal aflibercept in patients with neovascular age-related macular… (More)
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Highly Cited
2014
Highly Cited
2014
PURPOSE A head-to-head comparison was performed between vascular endothelial growth factor blockade and laser for treatment of… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Data comparing systemic exposure and systemic vascular endothelial growth factor (VEGF) suppression of ranibizumab… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE To evaluate intravitreal aflibercept injections (IAI; also called VEGF Trap-Eye) for patients with macular edema… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Docetaxel plus prednisone is standard first-line chemotherapy for men with metastatic castrate-resistant prostate… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVE Two similarly designed, phase-3 studies (VEGF Trap-Eye: Investigation of Efficacy and Safety in Wet AMD [VIEW 1, VIEW 2… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE Treatment for metastatic colorectal cancer (mCRC) commonly involves a fluoropyrimidine-based chemotherapy regimen such as… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE Antivascular endothelial growth factor (anti-VEGF) therapy is a promising treatment approach for patients with recurrent… (More)
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