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adenosylhomocysteinase activity

Known as: AdoHcyase activity, S-adenosyl-L-homocysteine hydrolase activity, adenosylhomocysteine hydrolase activity 
Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine. [EC:3.3.1.1]
National Institutes of Health

Papers overview

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2013
2013
A method for fluorescence sensing of adenosine and alkaline phosphatase based on the inhibition of S-adenosylhomocysteine hydrolase activity.
This study presents a simple fluorescent method for the sensitive and selective detection of adenosine, based on adenosine… Expand
Highly Cited
1995
Highly Cited
1995
Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death
We report the generation and characterization of mice lacking adenosine deaminase (ADA). In humans, absence of ADA causes severe… Expand
1994
1994
Differential distribution of purine metabolizing enzymes between glia and neurons.
Previous studies showed that in cultured chick ciliary ganglion neurons and CNS glia, adenosine can be synthesized by hydrolysis… Expand
1990
1990
Familial hypermethioninemia partially responsive to dietary restriction.
Hypermethioninemia and absolute methionine intolerance were observed in three siblings. These patients had several peculiar… Expand
1989
1989
Basis for resistance to 3-deazaaristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase, in human B-lymphoblasts.
Clones resistant to 3-deazaaristeromycin, a potent inhibitor of S-adenosylhomocysteine hydrolase, were selected from a nucleoside… Expand
1986
1986
Neplanocin A. Actions on S-adenosylhomocysteine hydrolase and on hormone synthesis by GH4C1 cells.
We have investigated the biochemical actions of Neplanocin A (Nepl A), a carbocyclic adenosine analog, on purified calf liver S… Expand
1985
1985
Regulation of biogenic amine methyltransferases by glucocorticoids via s-adenosylmethionine and its metabolizing enzymes, methionine adenosyltransferase and s-adenosylhomocysteine hydrolase
This report examines the possibility that glucocorticoids control the degradation of adrenal phenylethanolamine N… Expand
1983
1983
Effect of 2'-deoxycoformycin infusion on S-adenosylhomocysteine hydrolase and the amount of S-adenosylhomocysteine and related compounds in tissues of mice.
Mice were given constant infusions of the adenosine deaminase inhibitor, 2'-deoxycoformycin, by i.p. implantation of microosmotic… Expand
1978
1978
An adenosine 3':5'-monophosphate adenosine-binding protein from mouse liver. Association with S-adenosylhomocysteinase activity.
Cyclic AMP-binding proteins not associated with protein kinase activity have been described in various tissues [l-7 1. Most of… Expand
1976
1976
A sensitive isotopic assay method for S-adenosylhomocysteine hydrolase. Some properties of the enzyme from rat liver.
A rapid and sensitive isotopic method is presented for the assay of S-adenosylhomocysteine hydrolase (EC 3.3.1.1) activity, based… Expand
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