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Drug Resistance Mutations for Surveillance of Transmitted HIV-1 Drug-Resistance: 2009 Update
Programs that monitor local, national, and regional levels of transmitted HIV-1 drug resistance inform treatment guidelines and provide feedback on the success of HIV-1 treatment and preventionExpand
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The phylogenetic handbook : a practical approach to DNA and protein phylogeny
1. Basic concepts of molecular evolution Anne-Mieke Vandamme 2. Sequence databases Guy Bottu and Marc Van Ranst 3. Multiple alignment Des Higgins 4. Nucleotide substitution models Korbinian Strimmer,Expand
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The Phylogenetic Handbook: A Practical Approach to Phylogenetic Analysis and Hypothesis Testing
Part I. Introduction: 1. Basic concepts of molecular evolution Anne-Mieke Vandamme Part II. Data Preparation: 2. Sequence databases and database searching Guy Bottu, Marc Van Ranst and Philippe LemeyExpand
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Human T-lymphotropic virus 1: recent knowledge about an ancient infection.
Human T-lymphotropic virus 1 (HTLV-1) has infected human beings for thousands of years, but knowledge about the infection and its pathogenesis is only recently emerging. The virus can be transmittedExpand
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Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event
ABSTRACT Coronaviruses are enveloped, positive-stranded RNA viruses with a genome of approximately 30 kb. Based on genetic similarities, coronaviruses are classified into three groups. Two group 2Expand
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Tracing the origin and history of the HIV-2 epidemic
In this study we date the introduction of HIV-2 into the human population and estimate the epidemic history of HIV-2 subtype A in Guinea-Bissau, the putative geographic origin of HIV-2. TheExpand
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An automated genotyping system for analysis of HIV-1 and other microbial sequences
We develop an automated genotyping system that can be easily applied to HIV-1 and other rapidly evolving viral pathogens. Expand
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DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A
DEB025/Debio 025 (Alisporivir) is a cyclophilin (Cyp)-binding molecule with potent anti-hepatitis C virus (HCV) activity both in vitro and in vivo. It is currently being evaluated in phase IIExpand
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Genetic Variability and Molecular Evolution of the Human Respiratory Syncytial Virus Subgroup B Attachment G Protein
ABSTRACT Human respiratory syncytial virus (HRSV) is the most important cause of acute respiratory disease in infants. Two major subgroups (A and B) have been identified based on antigenicExpand
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Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management.
BACKGROUND Infection with drug-resistant human immunodeficiency virus type 1 (HIV-1) can impair the response to combination therapy. Widespread transmission of drug-resistant variants has theExpand
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