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activation of phospholipase C activity

Known as: phospholipase C activation 
The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2015
01219862015

Related topics

Related topics

1 relation

Broader (1)

phospholipase C-activating G-protein coupled receptor signaling pathway

Related mentions per year

Related mentions per year

1986-2016
19801990200020102020
activation of phospholipase C activity
phospholipase C-activating G-protein coupled receptor signaling pathway

Papers overview

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2015
2015
Inhibition of P2Y6 receptor-mediated phospholipase C activation and Ca(2+) signalling by prostaglandin E2 in J774 murine macrophages.
Extracellular nucleotides act as inflammatory mediators through activation of multiple purinoceptors. Under inflammatory… (More)
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Highly Cited
2006
Highly Cited
2006
Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta.
AMP-activated protein kinase (AMPK) is a sensor of cellular energy state in response to metabolic stress and other regulatory… (More)
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2001
2001
Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation.
The serotonin (5-HT)2A and 5-HT2C receptors share a high degree of sequence homology and have very similar pharmacological… (More)
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1995
1995
Aspartate mutation distinguishes ETA but not ETB receptor subtype-selective ligand binding while abolishing phospholipase C activation in both receptors.
The endothelin receptors, ETA and ETB, are G protein-coupled receptors (GPCR) that show distinctively different binding profiles… (More)
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1995
1995
Effects of oestradiol and tamoxifen on oxytocin-induced phospholipase C activation in human myometrial cells.
The role of oestradiol in the control of uterine responsiveness to oxytocin was investigated by measuring oxytocin-induced… (More)
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Highly Cited
1995
Highly Cited
1995
Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells.
The Alzheimer amyloid precursor protein (APP) undergoes complex processing resulting in the production of a 4-kDa amyloid peptide… (More)
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1994
1994
Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells.
Adenosine potentiates the stimulated release of mast cell mediators. Pharmacologic studies suggest the presence of two adenosine… (More)
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Highly Cited
1990
Highly Cited
1990
Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation.
Antiphosphotyrosine immunoblots were used to characterize tyrosine phosphorylated proteins after stimulation of the human TCR… (More)
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1989
1989
Muscarinic receptor regulation of cytoplasmic Ca2+ concentrations in human SK-N-SH neuroblastoma cells: Ca2+ requirements for phospholipase C activation.
The relationship between muscarinic receptor-mediated inositol lipid hydrolysis and the generation of Ca2+ signals has been… (More)
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1986
1986
Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet…
In platelets activated by thrombin, the hydrolysis of phosphatidylinositol 4,5-bisphosphate by phospholipase C produces inositol… (More)
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