actin filament depolymerization

Known as: actin depolymerization, actin depolymerizing activity 
Disassembly of actin filaments by the removal of actin monomers from a filament. [GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0204019752017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Actin-depolymerizing factor (ADF)/cofilins are small actin-binding proteins found in all eukaryotes. In vitro, ADF/cofilins… (More)
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Highly Cited
2005
Highly Cited
2005
The tight junction (TJ) determines epithelial barrier function. Actin depolymerization disrupts TJ structure and barrier function… (More)
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Highly Cited
2004
Highly Cited
2004
At the leading edge of a motile cell, actin polymerizes in close apposition to the plasma membrane. Here we ask how the machinery… (More)
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Highly Cited
2002
Highly Cited
2002
Tropomyosin binds to actin filaments and is implicated in stabilization of actin cytoskeleton. We examined biochemical and cell… (More)
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Highly Cited
2002
Highly Cited
2002
Signal perception and the integration of signals into networks that effect cellular changes is essential for all cells. The self… (More)
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Highly Cited
1999
Highly Cited
1999
Extracellular signals regulate actin dynamics through small GTPases of the Rho/Rac/Cdc42 (p21) family. Here we show that p21… (More)
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Highly Cited
1998
Highly Cited
1998
Rac is a small GTPase of the Rho family that mediates stimulus-induced actin cytoskeletal reorganization to generate lamellipodia… (More)
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Highly Cited
1997
Highly Cited
1997
In contrast to the slow rate of depolymerization of pure actin in vitro, populations of actin filaments in vivo turn over rapidly… (More)
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Highly Cited
1995
Highly Cited
1995
Although the actin cytoskeleton has been implicated in vesicle trafficking, docking and fusion, its site of action and relation… (More)
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Highly Cited
1993
Highly Cited
1993
Actin filaments are highly concentrated in postsynaptic densities at central excitatory synapses, but their influence on… (More)
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