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acrylonitrile metabolic process

Known as: acrylonitrile metabolism 
The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the… 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice.
Acrylonitrile (AN) is a rodent carcinogen and suspected human carcinogen. Metabolism of AN proceeds via conjugation with… 
2002
2002
CYTOCHROME P 450 2 E 1 ( CYP 2 E 1 ) IS ESSENTIAL FOR ACRYLONITRILE METABOLISM TO CYANIDE : COMPARATIVE STUDIES USING CYP 2 E 1-NULL AND WILD-TYPE MICE
Acrylonitrile (AN) is a rodent carcinogen and suspected human carcinogen. Metabolism of AN proceeds via conjugation with… 
2001
2001
Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile.
Review
2000
Review
2000
Species differences in acrylonitrile metabolism and toxicity between experimental animals and humans based on observations in human accidental poisonings
Abstract. The high acute toxicity of acrylonitrile may be a result of its intrinsic biological reactivity or of its metabolite… 
1988
1988
Consequences of acrylonitrile metabolism in rat hepatocytes: effects on lipid peroxidation and viability of the cells.
1984
1984
Interaction of acrylonitrile with the liver mixed function oxidases.
The effect on the liver mixed function oxidases of acrylonitrile revealed an inhibition of the benzo(a)pyrene hydroxylase and of… 
1981
1981
Evaluation of the role of acrylonitrile metabolism in the mechanism of its toxic action
1981
1981
[Evaluation of the role of acrylonitrile metabolism in the mechanism of its toxic action].
1980
1980
Two routes of acrylonitrile metabolism.
Acrylonitrile (AN) is metabolized in two different routes. The minor route of AN metabolism is its conversion to cyanide. In… 
1980
1980
New findings on acrylonitrile metabolism.
The mechanism of the metabolic pathway of acrylonitrile to cyanide (and subsequently to thiocyanate which is excreted in the… 
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