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acrihellin

Known as: 3 beta,5,14-trihydroxy-19-oxo-5 beta-bufa-20,22-dienolide-3-(3-methylcrotonate), Bufa-20,22-dienolide, 5,14-dihydroxy-3-((3-methyl-1-oxo-2-butenyl)oxy)-19-oxo-, (3beta,5beta)- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BufanolidesCardiotonic Agents

Papers overview

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1994
1994
[Inhibitory effects of 6 cardiac glycosides on sodium pump in sheep Purkinje fibers].
The inhibitory effects of 6 cardiac glycosides (digoxin, meproscillarin, acrihellin, deslanoside, ouabain, K-strophanthin) on… 
1991
1991
Effects of acrihellin, a new cardiosteroid, compared to digoxin, MDL 17043, and milrinone in the pentobarbital‐compromised dog
Acrihellin, digoxin, MDL 17043, and milrinone were administered intravenously in the anesthetized dog to compare their effects on… 
1987
1987
Acrihellin, a cardioactive steroid escaping from the organ-bath
Summary1.The concentration of acrihellin rapidly declines in oxygenated Tyrode-solution, because the compound escapes from the… 
1984
1984
[The pharmacology of a new cardiosteroid, a partially synthetic derivative of the aglycone hellebrigenin (acrihellin)].
3 beta,5,14-Trihydroxy-19-oxo-5 beta-bufa-20,22-dienolide 3-(3-methylcrotonate) (acrihellin, D 12 316) is according to chemical… 
1984
1984
Synthesis of orally active cardiosteroid derivatives.
Starting from hellebrigenin, orally cardiotonic active acylcardiosteroid derivatives have been synthesized. D 12316 (acrihellin… 
1983
1983
Effects of acrihellin on cardiac contractility in comparison to various inotropic interventions.
The inotropic effects of the new cardiotonic drug 3 beta,5,14-trihydroxy-19-oxo-5 beta-bufa-20,22-dienolide-3-(3-methylcrotonate… 
1983
1983
The influence of a new cardiotonic drug, acrihellin, on sinus node and the current underlying pacemaker activity of cardiac Purkinje fibres.
The spontaneous beating frequency of guinea pig sino-atrial preparations was observed under the influence of 3 beta, 5, 14… 
1983
1983
Voltage clamp study of the action of the new cardiotonic compound acrihellin on fast and slow inward currents in cardiac Purkinje fibres.
The action of 3 beta,5,14-trihydroxy-19-oxo-5 beta-bufa-20,22-dienolide-3-(3-methylcrotonate) (D 12316, acrihellin) on the fast… 
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