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aconiazide

Known as: 2-formylphenoxyacetic acid isonicotinylhydrazone 
A hydrazone derivative of isoniazid, used in the treatment and prophylaxis of tuberculosis.
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antitubercular Agentsisoniazid
analogs & derivatives

Papers overview

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2009
2009
STRUCTURAL CHARACTERIZATION AND TOXICITY STUDIES OF NOVEL ORGANOTIN ( IV ) COMPLEXES DERIVED FROM BENZOYLACETONE ISONICOTINYLHYDRAZONE ( H 2 BAS ) : X-RAY CRYSTAL STRUCTURE OF [ Me 2 Sn ( BAS )
Six organotin(IV) complexes, [RmSnCl2-m(BAS)], where Rm = Me2 (2), nBu2 (3), Ph2 (4), Me (5), nBu (6) and Ph (7) have been… 
1995
1995
Six-Month Toxicity Comparison of the Antituberculosis Drugs Aconiazide and Isoniazid in Fischer 344 Rats
Aconiazide, a hydrazone derivative of isoniazid, has been proposed for the treatment of tuberculosis. The toxicity of aconiazide… 
1995
1995
High-performance liquid chromatographic analysis of the antituberculosis drugs aconiazide and isoniazid.
1994
1994
Pharmacokinetic Evaluation of Aconiazide, A Potentially Less Toxic Isoniazid Prodrug
Study Objective. To determine the bioavailability and renal elimination of isoniazid, acetylisoniazid, monoacetylhydrazine… 
1993
1993
Fourteen-Day, Repeat-Dose Toxicity Evaluation of Aconiazide Administered Orally to Male and Female Fischer 344 Rats
Aconiazide, a hydrazone derivative of isoniazid, has been proposed for the treatment of tuberculosis. As a first step toward… 
1955
1955
FURTHER OBSERVATIONS ON THE ANTIBACTERIAL ACTIVITY TO MYCOBACTERIUM TUBERCULOSIS OF A DERIVATIVE OF ISONIAZID, o‐HYDROXYBENZAL ISONICOTINYLHYDRAZONE (NUPASAL‐213)
INTRODUCTION A previous report1 described the in vitro tuberculostatic activity, and, in some cases, the toxicity and in vivo… 
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