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aclidinium

Known as: (3-Carbamoyl-3,3-diphenylpropyl)ethyldimethylammonium 
 
National Institutes of Health

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30 ACTUAT aclidinium bromide 0.4 MG/ACTUAT Dry Powder Inhaler [Tudorza]aclidinium bromide

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Tudorza

Papers overview

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2017
2017
ACTIVATE: the effect of aclidinium/formoterol on hyperinflation, exercise capacity, and physical activity in patients with COPD
The Phase IV, 8-week, randomized, double-blind, placebo-controlled ACTIVATE study (NCT02424344) evaluated the effect of… Expand
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2017
2017
A randomised double-blind, placebo-controlled, long-term extension study of the efficacy, safety and tolerability of fixed-dose combinations of aclidinium/formoterol or monotherapy in the treatment…
INTRODUCTION Aclidinium bromide/formoterol fumarate (AB/FF) 400/12 μg efficacy and safety was demonstrated in two 6-month Phase… Expand
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2015
2015
Searching for the synergistic effect between aclidinium and formoterol: From bench to bedside.
Aim of our study was to understand if the interaction between aclidinium and formoterol administered at therapeutic doses leads… Expand
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2015
2015
Pharmacological assessment of the onset of action of aclidinium and glycopyrronium versus tiotropium in COPD patients and human isolated bronchi.
Preclinical studies suggested that aclidinium and glycopyrronium might have a faster onset of action than tiotropium. In this… Expand
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Review
2015
Review
2015
Diagnosis and Pharmacotherapy of Stable Chronic Obstructive Pulmonary Disease: The Finnish Guidelines
The Finnish Medical Society Duodecim initiated and managed the update of the Finnish national guideline for chronic obstructive… Expand
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Highly Cited
2013
Highly Cited
2013
Efficacy and Safety of Aclidinium Bromide Compared with Placebo and Tiotropium in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: Results from a 6-week, Randomized, Controlled…
Abstract Background: This randomized, double-blind, Phase IIIb study evaluated the 24-hour bronchodilatory efficacy of aclidinium… Expand
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2013
2013
ACCORD COPD II: A Randomized Clinical Trial to Evaluate the 12-Week Efficacy and Safety of Twice-Daily Aclidinium Bromide in Chronic Obstructive Pulmonary Disease Patients
Background and ObjectivesAclidinium bromide is a long-acting muscarinic antagonist approved for the long-term maintenance… Expand
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Highly Cited
2011
Highly Cited
2011
Aclidinium bromide improves exercise endurance and lung hyperinflation in patients with moderate to severe COPD.
BACKGROUND Static and dynamic lung hyperinflation are associated with exercise impairment and poor outcomes in COPD patients… Expand
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Highly Cited
2010
Highly Cited
2010
Aclidinium inhibits cholinergic and tobacco smoke-induced MUC5AC in human airways
Mucus hypersecretion and mucin MUC5AC overexpression are pathological features of chronic obstructive pulmonary disease (COPD… Expand
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Review
2008
Review
2008
Novel long‐acting bronchodilators for COPD and asthma
An important step in simplifying asthma and chronic obstructive pulmonary disease (COPD) management and improving adherence with… Expand
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