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aceclidine

Known as: 3-Acetoxyquinuclidine, 1-Azabicyclo(2.2.2)octan-3-ol, acetate (ester), 3-Quinuclidinol Acetate 
National Institutes of Health

Related topics

Related topics

8 relations
Aceclidine Salicylate

Narrower (4)

GlaucadrineGlaucostatGlaucotataceclidine hydrochloride

Broader (3)

MioticsParasympathomimetic AgentsQuinuclidines

Papers overview

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Highly Cited
2007
Highly Cited
2007
Estimation of Agonist Activity at G Protein-Coupled Receptors: Analysis of M2 Muscarinic Receptor Signaling through Gi/o,Gs, and G15
We developed novel methods for analyzing the concentration-response curve of an agonist to estimate the product of observed… 
Highly Cited
2003
Highly Cited
2003
Correlation between pK(a) and reactivity of quinuclidine-based catalysts in the Baylis-Hillman reaction: discovery of quinuclidine as optimum catalyst leading to substantial enhancement of scope.
The reactivity of a variety of quinuclidine-based catalysts in the Baylis-Hillman reaction has been examined, and a… 
1998
1998
1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists.
The acetyl group of the muscarinic agonist aceclidine 4 was replaced by various 1,2,5-thiadiazoles to provide a new series of… 
Highly Cited
1991
Highly Cited
1991
Differential smooth muscle-like contractile properties of trabecular meshwork and ciliary muscle.
Highly Cited
1986
Highly Cited
1986
The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide). A potent, specific muscarinic acetylcholine receptor agonist.
1986
1986
Central pressor effects induced by muscarinic receptor agonists: evidence for a predominant role of the M2 receptor subtype.
1984
1984
Effects of intracellular antibodies to cGMP on responses of cortical neurons of awake cats to extracellular application of muscarinic agonists
1976
1976
A new probe for heterogeneity in muscarinic receptors: 2-methyl-spiro-(1, 3-dioxolane-4, 3')-quinuclidine.
1976
1976
A study of muscarinic receptor heterogeneity with weak antagonists.
1975
1975
A theoretical and experimental study of the semirigid cholinergic agonist 3-acetoxyquinuclidine.
The interaction of the two enantiomens of 3-acetoxyquinuclidine (3-AcQ) and of its N-methyl derivative with the cholinergic… 
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