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aceclidine

Known as: 3-Acetoxyquinuclidine, 1-Azabicyclo(2.2.2)octan-3-ol, acetate (ester), 3-Quinuclidinol Acetate 
 
National Institutes of Health

Related topics

Related topics

8 relations
Aceclidine Salicylate

Narrower (4)

GlaucadrineGlaucostatGlaucotataceclidine hydrochloride

Broader (3)

MioticsParasympathomimetic AgentsQuinuclidines

Papers overview

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2007
2007
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
We developed novel methods for analyzing the concentration-response curve of an agonist to estimate the product of observed… Expand
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2003
2003
Correlation between pK(a) and reactivity of quinuclidine-based catalysts in the Baylis-Hillman reaction: discovery of quinuclidine as optimum catalyst leading to substantial enhancement of scope.
The reactivity of a variety of quinuclidine-based catalysts in the Baylis-Hillman reaction has been examined, and a… Expand
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1999
1999
Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats.
The purpose of our studies was to determine the effects of muscarinic receptor agonists on conditioned avoidance responding in… Expand
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1996
1996
The interaction of the enantiomers of aceclidine with subtypes of the muscarinic receptor.
The pharmacological activity of the enantiomers of aceclidine was investigated in Chinese hamster ovary cells transfected with… Expand
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1993
1993
Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists.
In primates, ciliary muscle contraction causes accommodation and facilitates aqueous outflow. In living rhesus monkeys… Expand
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Highly Cited
1991
Highly Cited
1991
Differential smooth muscle-like contractile properties of trabecular meshwork and ciliary muscle.
The contractile properties of bovine trabecular meshwork and ciliary muscle strips were investigated using an electromagnetic… Expand
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1990
1990
Dissociation between the effect of aceclidine on outflow facility and accommodation.
The dose/effect relationships for intracameral doses of aceclidine HCl and pilocarpine HCl on total facility of outflow and… Expand
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1989
1989
Hemicholinium-3 impairs spatial learning and the deficit is reversed by cholinomimetics
The effects of hemicholinium-3 (HC-3) on spatial discriminaton learning were studied. Rats were equipped with indwelling cannulae… Expand
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1986
1986
The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide). A potent, specific muscarinic acetylcholine receptor agonist.
The effects of the compound RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide) in a number of in vitro and… Expand
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1975
1975
Accommodative effects of aceclidine in the treatment of glaucoma.
In 18 patients, 2% pilocarpine, 2% pilocarpine plus tropicamide 10:1, and 2% aceclidine were tested with respect to the degree of… Expand
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