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Canonical inflammasome activation induces a caspase-1/gasdermin D (Gsdmd)–dependent lytic cell death called pyroptosis that… Expand In recent study, in order to improve the bioavailability of endomorphin-1 (EM-1), we designed and synthesized a series of novel… Expand Previous research has demonstrated that substance P N-terminal fragments produced by the action of several different enzymes in… Expand Background For a given subject, time in moderate to very vigorous intensity physical activity (MVPA) varies substantially among… Expand BACKGROUND
This study was designed to determine changes in nonadrenergic, noncholinergic (NANC) neurotransmission mediated by… Expand The endogenous μ-opioid receptor agonist, endomorphin (EM)-1, cannot be delivered into the central nervous system (CNS) in… Expand The peptide substance P (SP) is known to take part in the regulation of the Cl(-)-dependent secretion in the animal and human… Expand Neutrophil apoptosis is an important event in the resolution of inflammation. The role of substance P (SP) in neutrophil… Expand BACKGROUND & AIMS
Substance P, a member of the tachykinin family, is a prosecretory neuropeptide distributed widely throughout… Expand Rostral ventrolateral medulla (rVLM) and parapyramidal region (PPr) serve as important medullary control sites for… Expand