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ZNRF3 gene

Known as: ZNRF3, FLJ22057, RNF203 
This gene is involved in protein ubiquitination and Wnt pathway inhibition.
National Institutes of Health

Related topics

Related topics

4 relations
Signal Transduction InhibitionUbiquitinated Protein DegradationUbiquitinationZNRF4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma
Background: The prognosis of adrenocortical carcinoma (ACC) is heterogeneous. Genomic studies have identified ACC subgroups… 
2018
2018
Author Correction: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6
In this Letter, the surname of author Lena Vlaminck was misspelled ‘Vlaeminck’. In addition, author Kris Vleminckx should have… 
2016
2016
ZNRF3 contributes to the growth of lung carcinoma via inhibiting Wnt/β-catenin pathway and is regulated by miR-93
Lung carcinoma is the most common cancer with increasing morbidity, inefficient therapeutic modality, and poor prognosis, due to… 
2015
2015
Engineering High-Potency R-spondin Adult Stem Cell Growth Factors
Secreted R-spondin proteins (RSPOs1–4) function as adult stem cell growth factors by potentiating Wnt signaling. Simultaneous… 
2015
2015
Abstract C45: Phase I study of WNT974, a first-in-class Porcupine inhibitor, in advanced solid tumors
Background: Aberrant Wnt pathway activation is critical for initiation and maintenance of multiple tumor types, yet therapeutic… 
2015
2015
ZnRF3 induces apoptosis of gastric cancer cells by antagonizing Wnt and Hedgehog signaling.
AIM The aim of this paper was to investigate the function an importance of E3-ubiquitin ligase ZnRF3 in the progression of cancer… 
2015
2015
Anomalies moléculaires dans une large série de corticosurrénalomes stade III–IV : à la recherche de nouvelles options thérapeutiques
2013
2013
ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma
E3 ubiquitin ligases regulate a variety of biological processes through the ubiquitin–proteasome system, together with ubiquitin… 
2012
2012
Modulating WNT receptor turnover for tissue repair
New mechanistic insight into the regulation of WNT signaling supports efforts to target this pathway in adult stem cells for… 
2010
2010
ADAM28: A potential oncogene involved in asbestos‐related lung adenocarcinomas
Asbestos‐related lung cancer accounts for 4–12% of all lung cancers worldwide. Since putative mechanisms of carcinogenesis differ… 
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