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The pharmacological nature of nicotine-induced contraction in the rat basilar artery is poorly understood. The purpose of this… Expand 1. Noradrenaline (NA; 0.3 µmol/L) caused a contraction of the rat coronary artery that markedly increased in the presence of the… Expand 1. Arginine vasopressin (AVP) has been reported to be involved in the development of cerebral vasospasm after haemorrhage and… Expand 1. Previous studies have suggested the involvement of arginine vasopressin (AVP) and inflammation in the development of cerebral… Expand Nonredox type 5-lipoxygenase (5-LO) inhibitors, such as ZM 230487, its methyl analogue ZD 2138, or the Merck compound L-739,010… Expand This article reviews the literature on the effects of leukotrienes in asthma. In particular, the ability of recently developed… Expand 1 Leukotrienes have potent biological effects in vitro and in vivo and are found in tissue and in biological fluids in various… Expand 1 Mediators of inflammation can increase vascular permeability in at least two different ways: by acting directly on endothelial… Expand