ZK-EPO
National Institutes of Health
Papers overview
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BACKGROUND
Sagopilone (ZK-EPO) is a fully synthetic microtubule-stabilizing agent that has demonstrated high antitumor activity…
Resistance to chemotherapeutic agents is a significant obstacle to the effective treatment of metastatic breast cancer (MBC…
It has been demonstrated that sagopilone (ZK-EPO) has antitumor activity in human orthotopic glioma models in vitro and in vivo…
Background: Tubulin is among the most established and clinically validated targets in oncology. The taxanes, paclitaxel and…
BACKGROUND
Tubulin is among the most established and clinically validated targets in oncology. The taxanes, paclitaxel and…
Sagopilone (ZK-EPO) is the first fully synthetic epothilone undergoing clinical trials for the treatment of human tumors. Here…
5141 Background: The microtubule stabilizer docetaxel, in combination with prednisone, prolongs life in patients with metastatic…
19081 Background: Sagopilone, a novel epothilone, has shown preclinical activity against SCLC cell lines. A completed Phase I…
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the…