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ZD1694

Known as: ZD 1694, ZD-1694 
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Thymidylate synthase (TS) is an important target for cancer chemotherapy. However, several mechanisms of resistance to TS… 
Highly Cited
1999
Highly Cited
1999
Transfection of multidrug resistance proteins (MRPs) MRP1 and MRP2 in human ovarian carcinoma 2008 cells conferred a marked level… 
Review
1999
Review
1999
Thymidylate synthase (TS) is a critical enzyme for DNA replication and cell growth because it is the only de novo source of… 
Review
1997
Review
1997
PURPOSE AND METHODS Although fluoropyrimidines, in particular, fluorouracil (5-FU) and fluorodeoxyuridine (FdUrd), are active… 
Highly Cited
1997
Highly Cited
1997
ZD9331 is a drug that was developed from a potent class of water-soluble, C7-methyl-substituted, quinazoline-based inhibitors of… 
Review
1996
Review
1996
PURPOSE Tomudex (ZD1694; Zeneca Ltd, Macclesfield, United Kingdom) appears to have a favorable toxicity profile (defined in phase… 
Highly Cited
1995
Highly Cited
1995
Four cell lines, the mouse L1210 leukaemia, the human W1L2 lymphoblastoid and two human ovarian (CH1 and 41M) cell lines, were…