ZD1694

Known as: ZD 1694, ZD-1694 
 
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Transfection of multidrug resistance proteins (MRPs) MRP1 and MRP2 in human ovarian carcinoma 2008 cells conferred a marked level… (More)
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1996
1996
BACKGROUND Currently available therapies for advanced pancreatic cancer offer only palliative benefits, and patients with this… (More)
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1996
1996
The inhibition of thymidylate synthase (TS) as a drug development target has received much attention in recent years, and several… (More)
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1996
1996
ZD1694 (Tomudex; TDX) is a quinazoline antifolate that, when polyglutamated, is a potent inhibitor of thymidylate synthase (TS… (More)
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1996
1996
Using four complementary approaches, ie., cell synchronization, bromodeoxyuridine labeling, and DNA and Western blot analyses, we… (More)
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1996
1996
ZD1694 ('Tomudex'), a novel, direct and specific thymidylate synthase (TS) inhibitor, was developed in a collaborative research… (More)
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Review
1995
Review
1995
ZD1694 (Tomudex) is a new antifolate which is a specific inhibitor of thymidylate synthase (TS). Evidence suggests that ZD1694… (More)
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Highly Cited
1995
Highly Cited
1995
The transport properties and growth-inhibitory potential of 37 classic and novel antifolate compounds have been tested in vitro… (More)
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1995
1995
The patterns of DNA fragmentation were evaluated following a brief exposure (2 h) of the human ileocecal adenocarcinoma cell line… (More)
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1995
1995
Four cell lines, the mouse L1210 leukaemia, the human W1L2 lymphoblastoid and two human ovarian (CH1 and 41M) cell lines, were… (More)
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