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ZD 7288

Known as: ZD-7288, ZD7288, ZENECA ZD7288 
National Institutes of Health

Papers overview

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2012
2012
Identification of a hyperpolarization-activated cyclic nucleotide-gated channel and its subtypes in the urinary bladder of the rat.
2010
2010
Interneurons of the cerebellar cortex toggle Purkinje cells between up and down states
We demonstrate that single interneurons can toggle the output neurons of the cerebellar cortex (the Purkinje cells) between their… 
2007
2007
Mechanistic Role of If Revealed by Induction of Ventricular Automaticity by Somatic Gene Transfer of Gating-Engineered Pacemaker (HCN) Channels
Background— Although If, encoded by the hyperpolarization-activated cyclic-nucleotide-modulated (HCN) channel gene family, is… 
Highly Cited
2006
Highly Cited
2006
Distinct Populations of HCN Pacemaker Channels Produce Voltage-dependent and Voltage-independent Currents
Hyperpolarization-activated HCN pacemaker channels are critical for the generation of spontaneous activity and the regulation of… 
2005
2005
Peripheral Block of the Hyperpolarization-Activated Cation Current (Ih) Reduces Mechanical Allodynia in Animal Models of Postoperative and Neuropathic Pain
2005
2005
Neuromodulation by a cytokine: interferon-beta differentially augments neocortical neuronal activity and excitability.
The immunomodulatory cytokine interferon-beta (IFN-beta) is used in the treatment of autoimmune diseases such as multiple… 
2005
2005
Oscillatory activity within rat substantia gelatinosa in vitro: a role for chemical and electrical neurotransmission
Although rhythmic behaviour of mammalian spinal ventral horn networks has been extensively studied little is known about… 
Highly Cited
2004
Highly Cited
2004
ZD7288 inhibits postsynaptic glutamate receptor‐mediated responses at hippocampal perforant path–granule cell synapses
Hyperpolarization‐activated channels (Ih) are widely expressed in the nervous system and believed to play an important role in… 
2004
2004
Activity‐dependent excitability changes in hippocampal CA3 cell Schaffer axons
The membrane potential changes following action potentials in thin unmyelinated cortical axons with en passant boutons may be… 
2001
2001
NO-cGMP pathway increases the hyperpolarisation-activated current, I(f), and heart rate during adrenergic stimulation.
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