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ZCCHC8 gene

Known as: ZCCHC8, Zinc Finger, CCHC Domain Containing 8 Gene, zinc finger CCHC-type containing 8 
This gene plays a role in RNA binding.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The nuclear exosome and its essential co-factor, the RNA helicase MTR4, play crucial roles in several RNA degradation pathways… Expand
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2019
2019
Short telomere syndromes manifest as familial idiopathic pulmonary fibrosis; they are the most common premature aging disorders… Expand
2018
2018
  • M. Puno, C. Lima
  • Proceedings of the National Academy of Sciences
  • 2018
  • Corpus ID: 44121434
Significance Aberrant or unwanted transcripts can be degraded by the RNA exosome with the help of the nuclear exosome-targeting… Expand
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Highly Cited
2016
Highly Cited
2016
The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its co… Expand
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2016
2016
The eukaryotic RNA exosome participates extensively in RNA processing and degradation. In human cells, three accessory factors… Expand
2016
2016
Congenital gliobastoma multiforme (GBM) is rare and little is known about the molecular defects underlying the initiation and… Expand
2015
2015
The Nuclear Exosome Targeting (NEXT) complex is a key cofactor of the mammalian nuclear exosome in the removal of Promoter… Expand
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Highly Cited
2011
Highly Cited
2011
The RNA exosome is a conserved degradation machinery, which obtains full activity only when associated with cofactors. The most… Expand
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2006
2006
The NCps (nucleocapsid proteins) of HIV-1 (HIV type 1), HIV-2 and SIV (simian immunodeficiency virus) are small highly basic… Expand
2005
2005
Phosphorylation of c-Myc on threonine 58 (T58) stimulates its degradation by the Fbw7-SCF ubiquitin ligase. We used a… Expand