Z 338

Known as: Acotiamide, Z-338 
A prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet… (More)

Topic mentions per year

Topic mentions per year

1998-2018
05101519982018

Papers overview

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2011
2011
In clinical trials, acotiamide hydrochloride (acotiamide: Z-338) has been reported to be useful in the treatment of functional… (More)
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2011
2011
The novel gastroprokinetic agent acotiamide improves gastric motility by inhibiting acetylcholinesterase activity in stomach… (More)
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2011
2011
Acotiamide hydrochloride (acotiamide; N-[2-[bis(1-methylethyl) amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl) amino] thiazole-4… (More)
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2010
2010
BACKGROUND Acotiamide is a selective acetylcholinesterase inhibitor and enhances the actions of cholinergic neurons localized in… (More)
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2008
2008
Acotiamide hydrochloride (Z-338) is a member of new class prokinetic agents currently being developed for the treatment of… (More)
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2004
2004
This study characterized the functional effects of a novel gastroprokinetic agent, N-[2-(diisopropylamino)ethyl]-2-[(2-hydroxy-4… (More)
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2004
2004
Zeria and Yamanouchi are co-developing Z-338, a thiazole-4-carboxamide derivative with prokinetic activities, as a potential… (More)
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2002
2002
1. To study the mechanisms involved in the action of Z-338, a newly synthesized gastroprokinetic agent, experiments were… (More)
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2000
2000
We studied the effects of Z-338, a newly synthesized carboxyamide derivative, on autonomic neuroeffector transmission in the… (More)
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2000
2000
The mechanism by which Z-338, a novel gastroprokinetic agent, stimulates gastric motility was studied in relation to muscarinic… (More)
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