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YM-254890

Known as: YM254890 
National Institutes of Health

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Cyclic Peptides

Papers overview

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2019
2019
Structure–Activity Relationship Studies of the Natural Product Gq/11 Protein Inhibitor YM‐254890
G proteins act as molecular switches in G protein‐coupled receptor signaling pathways and are key mediators for numerous… 
2017
2017
The GABAB positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABAB receptors
2014
2014
Endothelin-1 activates extracellular signal-regulated kinases 1/2 via transactivation of platelet-derived growth factor receptor in rat L6 myoblasts.
2013
2013
Human airway trypsin-like protease induces mucin5AC hypersecretion via a protease-activated receptor 2-mediated pathway in human airway epithelial cells.
2013
2013
Dextran sulphate induces fibrinogen receptor activation through a novel Syk-independent PI-3 kinase-mediated tyrosine kinase pathway in platelets
Summary In our attempt to find a physiological agonist that activates PAR3 receptors, we screened several coagulation proteases… 
2011
2011
Protein kinase Cδ mediates the activation of protein kinase D2 in platelets.
2010
2010
P2Y2 Receptor-Gq/11 Signaling at Lipid Rafts Is Required for UTP-Induced Cell Migration in NG 108-15 Cells
Lipid rafts, formed by sphingolipids and cholesterol within the membrane bilayer, are believed to have a critical role in signal… 
2010
2010
Light induces Fos expression via extracellular signal‐regulated kinases 1/2 in melanopsin‐expressing PC12 cells
J. Neurochem. (2010) 112, 797–806. 
2009
2009
Multiple muscarinic pathways mediate the suppression of voltage‐gated Ca2+ channels in mouse intestinal smooth muscle cells
Background and purpose:  Stimulation of muscarinic receptors in intestinal smooth muscle cells results in suppression of voltage… 
2005
2005
The extracellular zinc-sensing receptor mediates intercellular communication by inducing ATP release.
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