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YM 12617

Known as: YM-12617 
 
National Institutes of Health

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3 relations

Broader (3)

Adrenergic alpha-AntagonistsSulfonamidesamsulosin

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1995
1995
Pharmacological characterization of noradrenaline-induced contractions of the porcine isolated palmar lateral vein and palmar common digital artery.
  • N A Blaylock, Vincent G Wilson
  • British journal of pharmacology
  • 1995
    • Corpus ID: 24771666
1. The aim of this study was to examine the pharmacological characteristics of alpha-adrenoceptor-mediated contractions in two… Expand
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1992
1992
Effect of the optical isomers of YM-12617 on increased intra-urethral pressure induced by phenylephrine in anaesthetized dogs.
1. Effects of the individual optical isomers of YM-12617 (R, S 5-[2-[[2-(o-ethoxyphenoxy)ethyl]-amino]propyl]-2… Expand
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1989
1989
Alpha 1-adrenoceptors: the ability of various agonists and antagonists to discriminate between two distinct [3H]prazosin binding sites.
Recently, it has been demonstrated that two distinct alpha 1-adrenoceptor binding sites showing high and low affinity for WB-4101… Expand
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1988
1988
Electrical and mechanical properties of the capsular smooth muscles of the rabbit prostate in relation to the actions of the alpha 1-adrenoceptor blocker, YM-12617.
1. Electrical and mechanical properties of smooth muscle cells of the rabbit prostate capsule and the actions of the alpha 1… Expand
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1987
1987
Further studies on (±)-YM-12617, a potent and selective α1-adrenoceptor antagonist and its individual optical enantiomers
SummaryYM-12617, 5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide HCl is structurally novel, an… Expand
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1987
1987
Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy.
Alpha-1 adrenoceptors in hypertrophied prostates of humans were characterized by a binding assay using [3H]prazosin as a… Expand
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1986
1986
Alpha-1 adrenoceptor antagonist effects of the optical isomers of YM-12617 in rabbit lower urinary tract and prostate.
The alpha-1 adrenoceptor antagonist effects of the optical isomers of YM-12617 (5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino]propyl]- 2… Expand
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1986
1986
A difference in mode of antagonism between optical isomers of a potent selective alpha 1-adrenoceptor blocker (YM-12617) and norepinephrine in isolated rabbit iris dilator and aorta.
Optical isomers of YM-12617, a potent and selective alpha 1-adrenoceptor blocker, were tested on the rabbit iris dilator and… Expand
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1985
1985
Studies on YM-12617: a selective and potent antagonist of postsynaptic alpha 1-adrenoceptors.
YM-12617, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]-amino]propyl]-2 -methoxybenzenesulfonamide HCl is a structurally new type of extremely… Expand
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1985
1985
Studies on YM-12617: A selective and potent antagonist of postsynaptic α1-adrenoceptors
SummaryYM-12617, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]-amino]propyl]-2-methoxybenzenesulfonamide HCl is a structurally new type of… Expand
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  • table 1
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  • figure 4
  • figure 5
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