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YM 12617

Known as: YM-12617 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Adrenergic alpha-AntagonistsSulfonamidesamsulosin

Papers overview

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2004
2004
Further studies on (±)-YM-12617, a potent and selective α1-adrenoceptor antagonist and its individual optical enantiomers
SummaryYM-12617, 5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide HCl is structurally novel, an… Expand
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2004
2004
Studies on YM-12617: A selective and potent antagonist of postsynaptic α1-adrenoceptors
SummaryYM-12617, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]-amino]propyl]-2-methoxybenzenesulfonamide HCl is a structurally new type of… Expand
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1996
1996
Effect of Maturation on α-Adrenoceptor Activity in Newborn Piglet Mesentery
Abstract To characterize the mesenteric α1- and α2-adrenoceptor populations in newborn piglets, an extracorporeal circuit was… Expand
1992
1992
Effect of the optical isomers of YM-12617 on increased intra-urethral pressure induced by phenylephrine in anaesthetized dogs.
1. Effects of the individual optical isomers of YM-12617 (R, S 5-[2-[[2-(o-ethoxyphenoxy)ethyl]-amino]propyl]-2… Expand
1988
1988
Electrical and mechanical properties of the capsular smooth muscles of the rabbit prostate in relation to the actions of the α1‐adrenoceptor blocker, YM‐12617
1 Electrical and mechanical properties of smooth muscle cells of the rabbit prostate capsule and the actions of the α1… Expand
Highly Cited
1987
Highly Cited
1987
Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy.
Alpha-1 adrenoceptors in hypertrophied prostates of humans were characterized by a binding assay using [3H]prazosin as a… Expand
Highly Cited
1986
Highly Cited
1986
Alpha-1 adrenoceptor antagonist effects of the optical isomers of YM-12617 in rabbit lower urinary tract and prostate.
The alpha-1 adrenoceptor antagonist effects of the optical isomers of YM-12617 (5-[2-[[2-(o-ethoxyphenoxy)ethyl]amino]propyl]- 2… Expand
1986
1986
A difference in mode of antagonism between optical isomers of a potent selective alpha 1-adrenoceptor blocker (YM-12617) and norepinephrine in isolated rabbit iris dilator and aorta.
Optical isomers of YM-12617, a potent and selective alpha 1-adrenoceptor blocker, were tested on the rabbit iris dilator and… Expand
1985
1985
Studies on YM-12617: a selective and potent antagonist of postsynaptic alpha 1-adrenoceptors.
YM-12617, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]-amino]propyl]-2 -methoxybenzenesulfonamide HCl is a structurally new type of extremely… Expand
1985
1985
Effects of YM-12617, an alpha adrenoceptor blocking agent, on electrical and mechanical properties of the guinea-pig mesenteric and pulmonary arteries.
The effects of YM-12617 on the electrophysiological properties of smooth muscle membranes and prejunctional nerve terminals and… Expand
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