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Y 27632

Known as: Y-27632, Y27632 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Poor survival of human embryonic stem (hES) cells after cell dissociation is an obstacle to research, hindering manipulations… Expand
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Highly Cited
2006
Highly Cited
2006
Rho-kinase inhibitor Y-27632 (Y-27) affects actomyosin cytoskeletal networks and has been shown to significantly increase outflow… Expand
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Highly Cited
2005
Highly Cited
2005
Increasing evidence suggests that mechanical cues inherent to the extracellular matrix (ECM) may be equally as critical as its… Expand
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Highly Cited
2003
Highly Cited
2003
Myelin-associated inhibitors limit axonal regeneration in the injured brain and spinal cord. A common target of many neurite… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE To elucidate the roles of Rho-associated protein kinase (ROCK) in regulating intraocular pressure (IOP) and outflow… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE The goal of this study was to investigate the role of Rho kinase in the modulation of aqueous humor outflow facility. Rho… Expand
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Highly Cited
2000
Highly Cited
2000
Y-27632 [(+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide++ + dihydrochloride] is widely used as a specific… Expand
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Highly Cited
2000
Highly Cited
2000
Publisher Summary This chapter discusses the use and properties of Rho kinase (ROCK)-specific inhibitor Y-27632. The chapter… Expand
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Highly Cited
1999
Highly Cited
1999
The actin cytoskeleton undergoes extensive remodeling during cell morphogenesis and motility. The small guanosine triphosphatase… Expand
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Highly Cited
1997
Highly Cited
1997
Abnormal smooth-muscle contractility may be a major cause of disease states such as hypertension, and a smooth-muscle relaxant… Expand
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