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Xanthines, systemic for obstructive airway disease

Known as: Xanthines 
National Institutes of Health

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Xanthines

Papers overview

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2020
2020
Modified graphene-silica as a sorbent for in-tube solid-phase microextraction coupled to liquid chromatography-tandem mass spectrometry. Determination of xanthines in coffee beverages.
Review
2018
Review
2018
Efficacy and safety profile of xanthines in COPD: a network meta-analysis
Theophylline can still have a role in the management of stable chronic obstructive pulmonary disease (COPD), but its use remains… 
Highly Cited
2010
Highly Cited
2010
Zirconia based monoliths used in hydrophilic-interaction chromatography for original selectivity of xanthines.
Highly Cited
2006
Highly Cited
2006
Improving Potency, Selectivity, and Water Solubility of Adenosine A1 Receptor Antagonists: Xanthines Modified at Position 3 and Related Pyrimido[1,2,3‐cd]purinediones
The structure–activity relationships of xanthine derivatives related to the adenosine A1 receptor antagonists 8‐cyclopentyl‐1,3… 
Highly Cited
2005
Highly Cited
2005
Comparative substrate recognition by bacterial and fungal purine transporters of the NAT/NCS2 family
We compared the interactions of purines and purine analogues with representative fungal and bacterial members of the widespread… 
2003
2003
Fast determination of catechins and xanthines in tea beverages by micellar electrokinetic chromatography.
Antioxidant properties and stimulating effects of green tea are related to its content of cathechins and xanthines; tea quality… 
Highly Cited
2002
Highly Cited
2002
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
In the search for improved selective antagonist ligands of the A2B adenosine receptor, which have the potential as antiasthmatic… 
2002
2002
CAFFEINE AND OTHER XANTHINES AS CYTOCHEMICAL BLOCKERS AND REMOVERS OF HETEROCYCLIC DNA INTERCALATORS FROM CHROMATIN
Caffeine (CAF) and other xanthines non‐covalently bind with the cationic fluorescent dye acridine orange (AO) and with other… 
Review
2001
Review
2001
Pharmacological treatment of the ion transport defect in cystic fibrosis
Cystic fibrosis (CF) is a lethal monogenetic disease characterised by impaired water and ion transport over epithelia. The lung… 
Highly Cited
1998
Highly Cited
1998
Mechanism-based inactivation of human cytochrome P450 1A2 by furafylline: detection of a 1:1 adduct to protein and evidence for the formation of a novel imidazomethide intermediate.
The rapid loss of human CYP1A2 (cytochrome P450 1A2) activity caused by the 8-methylxanthine furafylline is investigated with the… 
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