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XRCC2 protein, human

Known as: XRCC2, X-Ray Repair Cross Complementing Protein 2, X-Ray Repair, Complementing Defective, Repair In Chinese Hamster 
DNA repair protein XRCC2 (280 aa, ~32 kDa) is encoded by the human XRCC2 gene. This protein plays a role in DNA double-strand break repair.
National Institutes of Health

Related topics

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17 relations
Cell NucleusDNA RepairDNA Repair GeneDNA repair protein

Broader (1)

DNA-Binding Proteins

Papers overview

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2015
2015
Lack of an association between XRCC2 R188H polymorphisms and breast cancer: an update meta-analysis involving 35,422 subjects.
PURPOSE Several studies have investigated the associations between XRCC2 R188H polymorphism and the susceptibility to breast… 
2013
2013
Combining heavy ion radiation and artificial microRNAs to target the homologous recombination repair gene efficiently kills human tumor cells.
2012
2012
Assessment of genetic mutations in the XRCC2 coding region by high resolution melting curve analysis and the risk of differentiated thyroid carcinoma in Iran
Homologous recombination (HR) is the major pathway for repairing double strand breaks (DSBs) in eukaryotes and XRCC2 is an… 
2011
2011
Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.
2010
2010
XRCC2 Arg188His polymorphism is not directly associated with breast cancer risk: evidence from 37,369 subjects
Several common single-nucleotide polymorphisms (SNPs) within the XRCC2 gene have been identified as potential breast cancer… 
2006
2006
Genetic Polymorphisms in the DNA Double-Strand Break Repair Genes XRCC3, XRCC2, and NBS1 Are Not Associated with Acute Side Effects of Radiotherapy in Breast Cancer Patients
Clinical sensitivity to ionizing radiation varies considerably among patients, and radiation-induced adverse effects developing… 
2006
2006
Influence of polymorphisms in xenobiotic‐metabolizing genes and DNA‐repair genes on diepoxybutane‐induced SCE frequency
Analysis of the combined effects of polymorphisms in genes encoding xenobiotic metabolizing enzymes (XMEs) and DNA repair… 
2004
2004
Genetic Variations in XRCC 2 and XRCC 3 Are Not Associated with Endometrial Cancer Risk
Introduction Endometrial cancer is a component of hereditary nonpolyposis colorectal carcinoma, primarily the consequence of… 
2003
2003
A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks.
Homologous recombination repair (HRR) is required for both the repair of DNA double strand breaks (DSBs) and the maintenance of… 
2002
2002
A potential role for the XRCC 2 R 188 H polymorphic site in DNA-damage repair and breast cancer
An acquired genetic instability, resulting from the loss of some types of DNA repair, is an early event in the development of a… 
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