XRCC1 gene

Known as: X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 Gene, X-ray repair complementing defective repair in Chinese hamster cells 1, XRCC1 
This gene is involved in single-strand DNA break repair.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
PURPOSE Platinum agents cause DNA cross-linking and oxidative damage. Genetic polymorphisms of DNA repair genes are associated… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The study goal was to examine the association of three polymorphisms in the XRCC1 gene (Arg194Trp, Arg280His, and Arg399Gln… (More)
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
DNA repair plays a critical role in protecting the genome of the cell from insults of cancer-causing agents, such as those found… (More)
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
DNA repair genes have an important role in protecting individuals from cancer-causing agents. Polymorphisms in several DNA repair… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
X-ray repair cross complementing group 1 (XRCC1) encodes a protein involved in base excision repair. We examined the association… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Polymorphisms in several DNA repair genes have recently been identified, but little is known about their phenotypic significance… (More)
  • table I
  • table II
  • table III
  • table IV
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Gastric cancer remains the leading cause of cancer death in China and other countries in eastern Asia. Studies of gastric cancer… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Hereditary genetic defects in DNA repair lead to increased risk of cancer. Polymorphisms in several DNA repair genes have been… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Because reduced DNA repair capacity (phenotype) has been suggested as a risk factor for squamous cell carcinoma of the head and… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Poly(ADP-ribose) polymerase (PARP; EC 2.4.2.30) is a zinc-finger DNA-binding protein that detects and signals DNA strand breaks… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?