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XK 469

Known as: XK469R, XK469, R(+)XK469 
The racemic form of a synthetic quinoxaline phenoxypropionic acid derivative with antineoplastic properties. XK469R selectively inhibits… 
National Institutes of Health

Related topics

Related topics

8 relations
DNA Repair InhibitionDNA Replication InhibitionMultidrug Resistance Inhibition processNCIt Antineoplastic Agent Terminology

Broader (1)

Quinoxalines

Papers overview

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2007
2007
Remarkable electronic and steric effects in the nitrile biotransformations for the preparation of enantiopure functionalized carboxylic acids and amides: implication for an unsaturated carbon-carbon…
Biotransformations of various functionalized racemic nitriles catalyzed by Rhodococcus erythropolis AJ270, a nitrile hydratase… 
2003
2003
A Facile Solid-Phase Synthesis of Substituted 2(5H)-Furanones from Polymer-Supported α-Selenocarboxylic Acids
The synthesis of polystyrene-supported α-selenoacetic acid, α-selenopropionic acid, and α-selenophenylacetic acid is described… 
Highly Cited
2001
Highly Cited
2001
Crucial influence of solvent and chirality-the formation of helices and three-dimensional nets by hydrogen-bonded biimidazolate complexes.
Deprotonation and recrystallisation of racemic [Co(2,2'-biimidazole)3][NO3]3 by ammonia in water/dimethylformamide solutions gave… 
1997
1997
d-Methionine preparation from racemic methionines by Proteus vulgaris IAM 12003 with asymmetric degrading activity
Abstract The microbial degradation of l-methionine was investigated in order to develop a practical process for d-methionine… 
1996
1996
Site-specific modification of the human N-ras proto-oncogene with each diol epoxide metabolite of benzo[a]pyrene and thermal denaturation studies of the adducted duplexes.
The central adenine residue (A) of codon 61 in the human N-ras proto-oncogene, 5'-CGGACAAGAAG-3', has been modified with each… 
1988
1988
Preparation of an optically pure secondary alcohol of synthetic pyrethroids using microbial lipases
SummaryEnzyme-catalysed hydrolysis of esters of 4-hydroxy-3-methyl-2-(2-propynyl)-cyclopent-2-enone (HMPC) was examined for the… 
1987
1987
Microbiological systems in organic synthesis: preparation of racemic prenalterol utilizing Cunninghamella echinulata.
The fungal microorganism Cunninghamella echinulata was utilized to para-hydroxylate the synthetic substrate (+/-)-1… 
1984
1984
Hydrolysis of benzo[a]pyrene diol epoxide and its covalent binding to DNA proceed through similar rate-determining steps.
The mutagenic and carcinogenic metabolite of benzo[a]pyrene, (7R,8S)-dihydroxy-(9R,10R)-epoxy-7,8, 9,10-tetrahydrobenzo[a]pyrene… 
1980
1980
Synthesis and antitumor activity of cyclophosphamide analogues. 3. Preparation, molecular structure determination and anticancer screening of racemic cis- and trans-4-phenylcyclophosphamide.
Cyclization of racemic 3-amino-3-phenyl-1-propranol with bis(2-chloroethyl)phosphoramidic dichloride gave a diastereomeric… 
1979
1979
Platinum analogs of clinical interest.
Eight platinum analogs including complexes containing two isomeric forms of 1,2-diaminocyclohexane have received preliminary…