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WY-8678

Known as: WY 8678, WY8678 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

GuanabenzGuanabenz Acetate

Narrower (1)

Wytensin

Papers overview

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1982
1982
[Pharmacological studies of guanabenz: effects of the central nervous system].
The general pharmacological properties of guanabenz (Wy-8678), a new centrally acting antihypertensive agent, on the central… 
1982
1982
[Reproduction study of Guanabenz, a new antihypertensive agent (1) - fertility test in rats].
Guanabenz (WY-8678) was given to rats to examine its effects on their reproductive ability, dams and their fetuses. The drug was… 
1982
1982
[Reproduction study of Guanabenz, a new antihypertensive agent (2) - teratological test in rats].
Guanabenz (WY-8678) was given to pregnant rats to examine its effects on dams, their fetuses, and offspring. The drug was… 
1981
1981
Pharmacokinetic disposition of guanabenz in the rhesus monkey.
The pharmacokinetics of guanabenz (E-2,6-dichlorobenzylidene aminoguanidine acetate, Wy-8678) in rhesus monkeys given 14C-labeled… 
1980
1980
Relationship of guanabenz concentrations in brain and plasma to antihypertensive effect in the spontaneously hypertensive rat.
The antihypertensive agent guanabenz (E-2,6-dichlorobenzylidene aminoguanidine acetate. Wy-8678) was administered i.v. in single… 
1972
1972
A study of the bradycardic effect of the antihypertensive agent 2,6-dichlorobenzylidene aminoguanidine acetate (WY-8678) in the anesthetized dog.
1970
1970
General pharmacologic actions of the antihypertensive agent 2,6-dichlorobenzylidene aminoguanidine acetate (WY-8678).
Wy-8678 has been shown to lower blood pressure and heart rate in unanesthetized hypertensive animals. The present study describes… 
1970
1970
Inhibition of spontaneous sympathetic nerve activity by the antihypertensive agent Wy-8678.
1970
1970
Actions of the antihypertensive agent 2,6-dichlorobenzylidene amino guanidine acetate (WY-8678) on the cardiac conduction system.
1969
1969
2,6-Dichlorobenzylidene amino guanidine acetate (Wy-8678). A new hypotensive agent
Bei unanästhesierten Ratten und Hunden wurden die antihypertensiven Eigenschaften von 2,6-Dichlorobenzyliden-Aminoguanidin-Azetat… 
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