WWTR1 protein, human

Known as: TAZ - transcriptional coactivator with PDZ-binding motif protein, human, WW domain containing transcription regulator 1 protein, human, Transcriptional Coactivator with PDZ-Binding Motif 
WW domain-containing transcription regulator protein 1 (400 aa, ~44 kDa) is encoded by the human WWTR1 gene. This protein is involved in the… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
The Hippo pathway is important for regulating tissue homeostasis, and its dysregulation has been implicated in human cancer… (More)
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Highly Cited
2015
Highly Cited
2015
The transcriptional co-activators YAP and TAZ are key regulators of organ size and tissue homeostasis, and their dysregulation… (More)
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Highly Cited
2014
Highly Cited
2014
We investigated whether stem cells remember past physical signals and whether these can be exploited to dose cells mechanically… (More)
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Highly Cited
2012
Highly Cited
2012
The Hippo pathway is crucial in organ size control, and its dysregulation contributes to tumorigenesis. However, upstream signals… (More)
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Highly Cited
2011
Highly Cited
2011
Cells perceive their microenvironment not only through soluble signals but also through physical and mechanical cues, such as… (More)
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Highly Cited
2011
Highly Cited
2011
Cancer stem cells (CSCs) are proposed to drive tumor initiation and progression. Yet, our understanding of the cellular and… (More)
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Highly Cited
2010
Highly Cited
2010
Several developmental pathways contribute to processes that regulate tissue growth and organ size. The Hippo pathway has emerged… (More)
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Highly Cited
2008
Highly Cited
2008
Transforming growth fazctor-β (TGFβ) family members regulate many developmental and pathological events through Smad… (More)
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Highly Cited
2008
Highly Cited
2008
TAZ is a WW domain containing a transcription coactivator that modulates mesenchymal differentiation and development of multiple… (More)
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Highly Cited
2000
Highly Cited
2000
The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by… (More)
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