Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling

@inproceedings{Zhao2015RegulationOS,
  title={Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling},
  author={Yulei Zhao and Xiaolong Yang},
  booktitle={Oncotarget},
  year={2015}
}
Antitubulin drugs are commonly used for the treatment of numerous cancers. However, either the intrinsic or acquired resistances of patients to these drugs result in the failure of the treatment and high mortality of cancers. Therefore, identifying genes or signalling pathways involved in antitubulin drug resistances is critical for future successful treatment of cancers.TAZ (Transcriptional coactivator with PDZ-binding motif), which is a core component of the Hippo pathway, is overexpressed in… CONTINUE READING

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International journal of cancer • 2015
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