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WR-142,490

Known as: WR 142,490, WR142,490 
National Institutes of Health

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Mefloquine

Papers overview

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1980
1980
Chemosuppressive field trials in Thailand. IV. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by mefloquine (WR 142,490, A 4-quinolinemethanol).
The effect of various dosages of mefloquine hydrochloride (WR 142,490) and sulfadoxine-pyrimethamine in the suppression of… 
Highly Cited
1978
Highly Cited
1978
Antimalarial Activities of Various 4-Quinolinemethanols with Special Attention to WR-142,490 (Mefloquine)
Pilot appraisals of the activities of a selected group of 4-quinolinemethanols against acute Plasmodium falciparum infections in… 
1978
1978
Antimalarial Activities of the 4-Quinolinemethanols WR-184,806 and WR-226,253
WR-184,806 and WR-226,253, two 4-quinolinemethanols structurally similar to WR-142,490 (mefloquine), have been studied in depth… 
Highly Cited
1977
Highly Cited
1977
The chemotherapy of rodent malaria, XXVII. Studies on mefloquine (WR 142,490).
Mefloquine (WR 142,490) is a potent blood schizontocide active against drug-sensitive and drug-resistant lines of Plasmodium… 
1976
1976
Chloroquine-resistant falciparum malaria from Irian Jaya (Indonesian New Guinea).
A strain of Plasmodium falciparum, transmitted in Irian Jaya (Indonesian New Guinea) was isolated in 1974 and sent to the… 
Highly Cited
1975
Highly Cited
1975
Studies of the disposition and metabolism of mefloquine HCl (WR 142,490), a quinolinemethanol antimalarial, in the rat. Limited studies with an analog, WR 30,090.
The overall fate of the quinolinemethanol antimalarial, mefloquine-HCl [WR 142,490, erythro-DL-alpha-(2-piperidyl)-2,9-bis… 
Highly Cited
1975
Highly Cited
1975
Mefloquine (WR 142,490) in the treatment of human malaria
Mefloquine hydrochloride, a new 4-quinolinemethanol, was administered as a single oral dose to 47 volunteers infected with… 
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