Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 236,464,194 papers from all fields of science
Search
Sign In
Create Free Account
WR 1065
Known as:
2-((3- aminopropyl)amino)ethanethiol
, WR-1065
, WR1065
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
Broader (2)
Mercaptoethylamines
Radiation-Protective Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Abstract 2480: Low dose radiation- and thiol-induced effects on micronuclei formation following fractionated irradiation
J. Murley
,
Richard C. Miller
,
+5 authors
D. Grdina
2011
Corpus ID: 74780439
Exposure of cells to low doses of ionizing radiation (≤ 10 cGy) or amifostine induces pro-survival pathways that result in…
Expand
2010
2010
Abstract 507: Elevated manganese superoxide dismutase (SOD2) activity as a mechanism for the low dose dadiation- and thiol-induced adaptive responses in human RKO36 colon carcinoma cells and BFS2C…
J. Murley
,
K. Baker
,
Y. Kataoka
,
R. Weichselbaum
,
D. Grdina
2010
Corpus ID: 72634877
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Exposure of cells to low non-lethal doses of…
Expand
2005
2005
The Aminothiol WR-1 065 Protects T Lymphocytes from Ionizing Radiation-induced Deletions of the HPRT Gene 1
Ľ.
,
Scott
,
Clark
,
Richard
,
J.
,
Albertini
2005
Corpus ID: 41682420
Aminothiols, such as WR-2721 and its active free thiol, WR-1065, reduce mutations from ionizing radiation in exponentially…
Expand
2003
2003
Amifostine impairs p 53-mediated apoptosis of human myeloid leukemia cells
J. Acosta
,
C. Richard
,
+4 authors
J. León
2003
Corpus ID: 43204011
Amifostine is used as a cytoprotective agent in cancer treatments. Amifostine protects from apoptosis in some models and has been…
Expand
2001
2001
Phase I trial of a twice‐daily regimen of amifostine with ifosfamide, carboplatin, and etoposide chemotherapy in children with refractory carcinoma
M. Fouladi
,
D. Stempak
,
+5 authors
S. Baruchel
Cancer
2001
Corpus ID: 24185555
Amifostine protects normal tissues against chemotherapy and radiation‐induced toxicity without loss of antitumor effects…
Expand
1994
1994
Molecular radioprotection of DNA by cysteamine and WR-1065 : a transient electric birefringence study
G. Mallet
,
K. Abdallah
,
A. Costa
,
D. Vasilescu
1994
Corpus ID: 89431973
The objective of the present «in vitro» study was to determine the molecular DNA radioprotection by the aminothiols cysteamine…
Expand
1994
1994
[Decrease of toxic effects of aminothiol radiation-protective agents and increase of chemical protection action against ionizing radiation by the use of unithiol].
S. Grachev
,
A. Sverdlov
,
N. G. Nikanorova
,
O. I. Bol'shakova
,
I. K. Korolva
Radiatsionnaia biologiia, radioecologiia
1994
Corpus ID: 5978262
It has been shown that unithiol diminishes toxic action of cysteamine, AET, and disulfide of WR-1065 on mice. This permits to…
Expand
1992
1992
Creatinine phosphokinase and cardiotoxicity in adriamycin chemotherapy and its modification by WR-1065
P. Bhanumathi
,
E. B. Saleesh
,
D. Vasudevan
1992
Corpus ID: 88814122
1987
1987
Interaction of DNA with the radioprotectors cysteamine and WR-1065: a Kerr effect study
G. Mallet
,
J. Lematre
,
M. Leca
,
D. Vasilescu
1987
Corpus ID: 99175147
1986
1986
Measurement of WR-1065 in plasma: preliminary pharmacokinetics in the beagle.
N. F. Swynnerton
,
B. K. Huelle
,
E. McGovern
,
D. J. Mangold
,
T. Ludden
Research communications in chemical pathology and…
1986
Corpus ID: 29764382
Described is a high-performance liquid chromatographic (HPLC) method for the quantification of WR-1065 [2-(3-aminopropylamino…
Expand