WR 1065

Known as: 2-((3- aminopropyl)amino)ethanethiol, WR-1065, WR1065 
 
National Institutes of Health

Papers overview

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2001
2001
The aminothiol WR-1065 (the active form of amifostine) protects normal tissues from the toxic effects of certain cancer drugs… (More)
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1996
1996
Although the aminothiol WR-1065 protects normal tissues, its direct effect on the damage and restoration of the vascular… (More)
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1996
1996
Normal tissue toxicity limits radiation therapy and could depend on the extent of damage to the vascular endothelium Aminothiols… (More)
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1992
1992
Our previous studies in mice demonstrated that systemic or topical 16,16 dm PGE2 protected against single dose radiation-induced… (More)
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1992
1992
Gamma-irradiation, glucocorticoid hormones, and calcium ionophores stimulate a suicide process in thymocytes, known as apoptosis… (More)
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1990
1990
The pharmacokinetics of WR-1065 [S-2-(3-aminopropylamino)ethanethiol] were investigated following iv, intraduodenal, and… (More)
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Highly Cited
1985
Highly Cited
1985
Addition of alkaline phosphatase and WR-2721 to culture medium containing V79-171 cells leads to production of WR-1065 and its… (More)
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1984
1984
Levels of reduced glutathione (GSH) and N-(2-mercaptoethyl)-1,3-diaminopropane (WR-1065) were measured in tissues of Balb/c mouse… (More)
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1984
1984
WR-1065, the dephosphorylated sulfhydryl form of WR-2721 has been suggested as the metabolite responsible for the radioprotective… (More)
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1983
1983
An isothermal microcalorimeter was used to measure changes in heat flow when radioprotective drugs were added to cultured… (More)
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