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WNT4 gene

Known as: Wnt family member 4, WINGLESS-TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 4, Wingless-Type MMTV Integration Site Family, Member 4 Gene 
This gene plays a role in hormonal signaling and is involved in sex determination.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Fate ControlEmbryonic DevelopmentIntercellular Communication ProcessPattern Formation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
The role of gene polymorphisms in endometriosis
Endometriosis is a benign gynecologic disorder, affecting up to 10% of women, characterized by the presence of functional… 
Highly Cited
2015
Highly Cited
2015
Systematic Mapping of WNT-FZD Protein Interactions Reveals Functional Selectivity by Distinct WNT-FZD Pairs*
Background: WNT-FZD specificity and signaling outcome have not been systematically mapped so far. Results: WNTs show selective… 
2015
2015
Analysis of WNT4 polymorphism in Chinese Han women with endometriosis.
2015
2015
Association of WNT4 polymorphisms with endometriosis in infertile patients
PurposeRecently, several genome-wide association studies have demonstrated an association between endometriosis and markers… 
Highly Cited
2013
Highly Cited
2013
Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease
Background WNT signalling is activated during lung tissue damage and inflammation. We investigated whether lung epithelial… 
2013
2013
Contribution of genetic and epigenetic mechanisms to Wnt pathway activity in prevalent skeletal disorders.
2011
2011
Exendin-4 upregulates the expression of Wnt-4, a novel regulator of pancreatic β-cell proliferation.
The Wnt-signaling pathway regulates β-cell functions. It is not known how the expression of endogenous Wnt-signaling molecules is… 
2009
2009
The human and mouse sex-determining SRY genes repress the Rspol/beta-catenin signaling.
2009
2009
Variation in WNT genes expression in different subtypes of chronic lymphocytic leukemia
The Wnt molecules are a family of secretory glycoproteins implicated in proliferation and differentiation of both normal and… 
Highly Cited
2004
Highly Cited
2004
Mutations in the SRY, DAX1, SF1 and WNT4 genes in Brazilian sex-reversed patients.
In most mammals, male development is triggered by the transient expression of the SRY gene, which initiates a cascade of gene… 
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