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WD40 Repeats

Known as: Repeats, beta-Transducin, Motifs, WD40, beta-Transducin Repeats 
WD40 Repeats are found in signal transduction, mRNA processing, cytoskeletal assembly, and cell cycle proteins; none are catalytic. G-beta is the… 
National Institutes of Health

Related topics

Related topics

32 relations
ATG16L1 protein, humanCHS proteinDCAF11 geneDCAF4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7.
Highly Cited
2006
Highly Cited
2006
The WD40 Repeats of FANCL Are Required for Fanconi Anemia Core Complex Assembly*
Fanconi anemia (FA) is an autosomal recessive disorder characterized by aplastic anemia, cancer susceptibility, and cellular… 
2006
2006
Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes.
Transforming growth factor-beta (TGF-beta) plays an essential role in chondrocyte maturation. It stimulates chondrocyte… 
2005
2005
Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100.
Processing of NF-kappaB2 precursor protein p100 to generate p52 is tightly controlled, which is important for proper function of… 
Highly Cited
2004
Highly Cited
2004
Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappaB in colorectal cancer.
BACKGROUND The ubiquitin-proteasome pathway is important in regulating protein signaling pathways that are involved in… 
2004
2004
HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates.
The human immunodeficiency virus type 1 Vpu protein acts as an adaptor for the proteasomal degradation of CD4 by recruiting CD4… 
Highly Cited
2002
Highly Cited
2002
Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC
Aberrant activation of the Wnt signaling pathway has been reported in different human tumor types, including malignant melanomas… 
1999
1999
WD Repeats of the p48 Subunit of Chicken Chromatin Assembly Factor-1 Required for in Vitro Interaction with Chicken Histone Deacetylase-2*
Chromatin assembly factor-1 (CAF-1) is essential for chromatin assembly in eukaryotes, and comprises three subunits of 150 kDa… 
1999
1999
beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta.
We have examined the role of beta-TrCP (beta-transducin repeat-containing protein) in the ubiquitination and degradation of… 
Highly Cited
1993
Highly Cited
1993
Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats
We have constructed a Xenopus oocyte cDNA library in a Saccharomyces cerevisiae expression vector and used this library to… 
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