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WD40 Repeats

Known as: Repeats, beta-Transducin, Motifs, WD40, beta-Transducin Repeats 
WD40 Repeats are found in signal transduction, mRNA processing, cytoskeletal assembly, and cell cycle proteins; none are catalytic. G-beta is the… Expand
National Institutes of Health

Related topics

Related topics

32 relations
ATG16L1 protein, humanCHS proteinDCAF11 geneDCAF4 gene
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network
The embryonic stem (ES) cell transcriptional and chromatin-modifying networks are critical for self-renewal maintenance. However… Expand
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Highly Cited
2010
Highly Cited
2010
MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro
A chronic proinflammatory state precedes pathological change in arterial endothelial cells located within regions of… Expand
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Highly Cited
2009
Highly Cited
2009
HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes*
Bone marrow stromal antigen 2 (BST-2, also known as tetherin) is a recently identified interferon-inducible host restriction… Expand
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Highly Cited
2007
Highly Cited
2007
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Aberrant WNT signal transduction is involved in many diseases. In colorectal cancer and melanoma, mutational disruption of… Expand
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Highly Cited
2001
Highly Cited
2001
Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1.
Arabidopsis COP1 is a photomorphogenesis repressor capable of directly interacting with the photomorphogenesis-promoting factor… Expand
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Highly Cited
1999
Highly Cited
1999
The TRANSPARENT TESTA GLABRA1 Locus, Which Regulates Trichome Differentiation and Anthocyanin Biosynthesis in Arabidopsis, Encodes a WD40 Repeat Protein
The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the… Expand
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Review
1999
Review
1999
The tetratricopeptide repeat: a structural motif mediating protein-protein interactions.
The tetratricopeptide repeat (TPR) motif is a protein-protein interaction module found in multiple copies in a number of… Expand
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Review
1999
Review
1999
Signaling through beta-catenin and Lef/Tcf.
Beta-catenin plays a structural role in cell adhesion by binding to cadherins at the intracellular surface of the plasma membrane… Expand
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Highly Cited
1998
Highly Cited
1998
Katanin, a Microtubule-Severing Protein, Is a Novel AAA ATPase that Targets to the Centrosome Using a WD40-Containing Subunit
Microtubule disassembly at centrosomes is involved in mitotic spindle function. The microtubule-severing protein katanin, a… Expand
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Highly Cited
1998
Highly Cited
1998
The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions.
The tetratricopeptide repeat (TPR) is a degenerate 34 amino acid sequence identified in a wide variety of proteins, present in… Expand
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