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WD40 Repeats

Known as: Repeats, beta-Transducin, Motifs, WD40, beta-Transducin Repeats 
WD40 Repeats are found in signal transduction, mRNA processing, cytoskeletal assembly, and cell cycle proteins; none are catalytic. G-beta is the… 
National Institutes of Health

Related topics

Related topics

32 relations
ATG16L1 protein, humanCHS proteinDCAF11 geneDCAF4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7.
2014
2014
Defining the Interactions and Role of DCAF1/VPRBP in the DDB1-Cullin4A E3 Ubiquitin Ligase Complex Engaged by HIV-1 Vpr to Induce a G2 Cell Cycle Arrest
HIV viral protein R (Vpr) induces a cell cycle arrest at the G2/M phase by activating the ATR DNA damage/replication stress… 
Highly Cited
2006
Highly Cited
2006
The WD40 Repeats of FANCL Are Required for Fanconi Anemia Core Complex Assembly*
Fanconi anemia (FA) is an autosomal recessive disorder characterized by aplastic anemia, cancer susceptibility, and cellular… 
2005
2005
Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100.
Processing of NF-kappaB2 precursor protein p100 to generate p52 is tightly controlled, which is important for proper function of… 
2004
2004
Tax deregulation of NF-kappaB2 p100 processing involves both beta-TrCP-dependent and -independent mechanisms.
Processing of the nf-kappab2 gene product p100 to generate p52 is a tightly regulated event, consistent with the fact that the… 
Highly Cited
2002
Highly Cited
2002
Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC
Aberrant activation of the Wnt signaling pathway has been reported in different human tumor types, including malignant melanomas… 
1999
1999
WD Repeats of the p48 Subunit of Chicken Chromatin Assembly Factor-1 Required for in Vitro Interaction with Chicken Histone Deacetylase-2*
Chromatin assembly factor-1 (CAF-1) is essential for chromatin assembly in eukaryotes, and comprises three subunits of 150 kDa… 
1999
1999
beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta.
We have examined the role of beta-TrCP (beta-transducin repeat-containing protein) in the ubiquitination and degradation of… 
1997
1997
Molecular genetic elucidation of the tripartite structure of the Schizosaccharomyces pombe 72 kDa TFIID subunit which contains a WD40 structural motif
Background: The multisubunit general transcription factor termed TFIID is comprised of the TATA box DNA binding protein TBP and… 
Highly Cited
1993
Highly Cited
1993
Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats
We have constructed a Xenopus oocyte cDNA library in a Saccharomyces cerevisiae expression vector and used this library to… 
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