Viomycin

Known as: Viomycine, Viomicin, Florimycin 
A strongly basic peptide, antibiotic complex from several strains of Streptomyces. It is allergenic and toxic to kidneys and the labyrinth. Viomycin… (More)
National Institutes of Health

Related topics

Related topics

17 relations

Broader (3)

Anti-Bacterial AgentsAntibiotics, AntitubercularProtein Synthesis Inhibitors
Antimycobacterial drug poisoningIn BloodViomycin SulfateViomycin:Susc:Pt:Isolate:OrdQn:MIC
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Narrower (3)

CP 101680VinactaneViocin

Papers overview

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Highly Cited
2010
Highly Cited
2010
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
Viomycin and capreomycin belong to the tuberactinomycin family of antibiotics, which are among the most effective antibiotics… (More)
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Highly Cited
2007
Highly Cited
2007
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
During protein synthesis, transfer RNA and messenger RNA undergo coupled translocation through the ribosome's A, P and E sites, a… (More)
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Highly Cited
2007
Highly Cited
2007
Kinetically competent intermediates in the translocation step of protein synthesis.
Translocation requires large-scale movements of ribosome-bound tRNAs. Using tRNAs that are proflavin labeled and single-turnover… (More)
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Highly Cited
2006
Highly Cited
2006
Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs.
The cyclic peptide antibiotics capreomycin and viomycin are generally effective against the bacterial pathogen Mycobacterium… (More)
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Highly Cited
2005
Highly Cited
2005
Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis.
Capreomycin, kanamycin, amikacin, and viomycin are drugs that are used to treat multidrug-resistant tuberculosis. Each inhibits… (More)
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2003
2003
Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster.
The tuberactinomycin antibiotics are essential components in the drug arsenal against Mycobacterium tuberculosis infections and… (More)
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Highly Cited
1997
Highly Cited
1997
Antibiotic resistance gene cassettes derived from the omega interposon for use in E. coli and Streptomyces.
Three antibiotic resistance gene cassettes, derived from the omega interposon (Prentki and Krisch (1984) Gene 29, 303-313) were… (More)
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Highly Cited
1987
Highly Cited
1987
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA.
Using dimethyl sulfate and kethoxal, we have probed antibiotic-ribosome complexes, and identified sites of interaction of… (More)
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Highly Cited
1982
Highly Cited
1982
pIJ101, a multi-copy broad host-range Streptomyces plasmid: Functional analysis and development of DNA cloning vectors
Streptomyces lividans ISP 5434 contains four small high copy number plasmids: pIJ101 (8.9 kb), pIJ102 (4.0 kb), pIJ103 (3.9 kb… (More)
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1978
1978
Resistance to viomycin conferred by RNA of either ribosomal subunit
THE basic peptide antibiotic viomycin inhibits prokaryotic protein biosynthesis1,2, and seems to bind at least to the small… (More)
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