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Viomycin

Known as: Viomycine, Viomicin, Florimycin 
A strongly basic peptide, antibiotic complex from several strains of Streptomyces. It is allergenic and toxic to kidneys and the labyrinth. Viomycin… Expand
National Institutes of Health

Related topics

Related topics

18 relations

Broader (4)

Anti-Bacterial AgentsAntibiotics, AntitubercularProtein Synthesis InhibitorsViomycins
Antimycobacterial drug poisoningIn BloodViomycin SulfateViomycin:Susc:Pt:Isolate:OrdQn:MIC
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Narrower (3)

CP 101680VinactaneViocin

Papers overview

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Highly Cited
2010
Highly Cited
2010
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
Viomycin and capreomycin belong to the tuberactinomycin family of antibiotics, which are among the most effective antibiotics… Expand
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Highly Cited
2007
Highly Cited
2007
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
During protein synthesis, transfer RNA and messenger RNA undergo coupled translocation through the ribosome's A, P and E sites, a… Expand
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Highly Cited
2007
Highly Cited
2007
Kinetically competent intermediates in the translocation step of protein synthesis.
Translocation requires large-scale movements of ribosome-bound tRNAs. Using tRNAs that are proflavin labeled and single-turnover… Expand
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Highly Cited
2005
Highly Cited
2005
Molecular Analysis of Cross-Resistance to Capreomycin, Kanamycin, Amikacin, and Viomycin in Mycobacterium tuberculosis
ABSTRACT Capreomycin, kanamycin, amikacin, and viomycin are drugs that are used to treat multidrug-resistant tuberculosis. Each… Expand
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Highly Cited
2003
Highly Cited
2003
Deciphering Tuberactinomycin Biosynthesis: Isolation, Sequencing, and Annotation of the Viomycin Biosynthetic Gene Cluster
ABSTRACT The tuberactinomycin antibiotics are essential components in the drug arsenal against Mycobacterium tuberculosis… Expand
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Highly Cited
1987
Highly Cited
1987
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA.
Using dimethyl sulfate and kethoxal, we have probed antibiotic-ribosome complexes, and identified sites of interaction of… Expand
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Highly Cited
1987
Highly Cited
1987
The aacA-aphD gentamicin and kanamycin resistance determinant of Tn4001 from Staphylococcus aureus: expression and nucleotide sequence analysis.
The aacA-aphD aminoglycoside resistance determinant of the Staphylococcus aureus transposon Tn4001, which specifies resistance to… Expand
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Highly Cited
1982
Highly Cited
1982
Cloning of antibiotic resistance and nutritional genes in streptomycetes.
Methodology which allows consistent shotgun cloning of streptomycete genes is presented. Parameters that increase transformation… Expand
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Highly Cited
1980
Highly Cited
1980
Mechanism of inhibition of translocation by kanamycin and viomycin: a comparative study with fusidic acid.
Abstract Kanamycin and viomycin were found to block a single cycle of translocation on the poly[U]-ribosome, carrying N-acetyl… Expand
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Highly Cited
1977
Highly Cited
1977
The inhibition of ribosomal translocation by viomycin.
The basic peptide antibiotic viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia… Expand
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