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Valine-tRNA Ligase
Known as:
L-Valine:tRNA(Val) ligase (AMP-forming)
, Ligase, Valine-tRNA
, Synthetase, Valyl-tRNA
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An enzyme that activates valine with its specific transfer RNA. EC 6.1.1.9
National Institutes of Health
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Related topics
Related topics
8 relations
In Blood
Process of secretion
VARS gene
antagonists & inhibitors
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Papers overview
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Highly Cited
2002
Highly Cited
2002
Plasticity of Recognition of the 3′-End of Mischarged tRNA by Class I Aminoacyl-tRNA Synthetases*
B. Nordin
,
P. Schimmel
Journal of Biological Chemistry
2002
Corpus ID: 1154750
Certain aminoacyl-tRNA synthetases prevent potential errors in protein synthesis through deacylation of mischarged tRNAs. For…
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Highly Cited
1991
Highly Cited
1991
Phosphorylation of valyl-tRNA synthetase and elongation factor 1 in response to phorbol esters is associated with stimulation of both activities.
R. Venema
,
H. Peters
,
J. Traugh
Journal of Biological Chemistry
1991
Corpus ID: 11250010
Highly Cited
1989
Highly Cited
1989
Valyl-tRNA synthetase from rabbit liver. I. Purification as a heterotypic complex in association with elongation factor 1.
G. Bec
,
P. Kerjan
,
X. Zha
,
J. Waller
Journal of Biological Chemistry
1989
Corpus ID: 23051868
Highly Cited
1979
Highly Cited
1979
Establishing the misacylation/deacylation of the tRNA pathway for the editing mechanism of prokaryotic and eukaryotic valyl-tRNA synthetases.
A. Fersht
,
C. Dingwall
Biochemistry
1979
Corpus ID: 654019
The valyl-tRNA synthetases from Bacillus stearothermophilus and Escherichia coli have been shown to edit the mistaken activation…
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Highly Cited
1976
Highly Cited
1976
Complete purification and studies on the structural and kinetic properties of two forms of yeast valyl-tRNA synthetase.
D. Kern
,
R. Giegé
,
S. Robre-Saul
,
Y. Boulanger
,
J. Ebel
Biochimie
1976
Corpus ID: 4913642
Highly Cited
1974
Highly Cited
1974
Incorrect aminoacylations involving tRNAs or valyl-tRNA synthetase from Bacillus stearothermophilus.
R. Giegé
,
D. Kern
,
J. Ebel
,
H. Grosjean
,
S. de Henau
,
H. Chantrenne
European Journal of Biochemistry
1974
Corpus ID: 41222540
Numerous misacylations occur on heterologous systems containing unfractionated tRNAs from yeast or from Bacillus…
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1973
1973
TYMV valyl-RNA as an amino-acid donor in protein biosynthesis.
A. Haenni
,
A. Prochiantz
,
O. Bernard
,
F. Chapeville
Nature: New biology
1973
Corpus ID: 11988819
THE observation that turnip yellow mosaic virus (TYMV) RNA (of sedimentation constant 23–25S) appears to have a tRNA-like…
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Highly Cited
1972
Highly Cited
1972
Accumulation and turnover of guanosine tetraphosphate in Escherichia coli.
N. Fiil
,
K. Meyenburg
,
J. Friesen
Journal of Molecular Biology
1972
Corpus ID: 46405636
1972
1972
Incorrect aminoacylations catalysed by E. coli valyl-tRNA synthetase.
R. Giegé
,
D. Kern
,
J. Ebel
Biochimie
1972
Corpus ID: 11321894
Highly Cited
1972
Highly Cited
1972
Incorrect aminoacylatins catalysed by the phenylalanyl-and valyl-tRNA synthetases from yeast.
D. Kern
,
R. Giegé
,
J. Ebel
European Journal of Biochemistry
1972
Corpus ID: 1149105
It has been found that purified phenylalanyl- and valyl-tRNA synthetases from yeast catalyse the mischarging of numerous…
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