Vaccines, DNA

Known as: DNA Vaccines, DNA Vaccine, vaccine dna 
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the… (More)
National Institutes of Health

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21 relations

Narrower (10)

BHT 3009BMP-PEI-pSLC-E7-Fc vaccineDNA-rAd5 vaccinePfCSP DNA vaccine
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In BloodMicrobiologicalProcess of secretionagonists
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Broader (2)

Nucleic Acid VaccinesPolynucleotide Vaccines

Papers overview

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Review
2017
Review
2017
Vaccines licensed and in clinical trials for the prevention of dengue.
Dengue has become a major global public health threat with almost half of the world's population living in at-risk areas… (More)
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Review
2011
Review
2011
Electroporation delivery of DNA vaccines: prospects for success.
A number of noteworthy technology advances in DNA vaccines research and development over the past few years have led to the… (More)
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Highly Cited
2008
Highly Cited
2008
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
Successful vaccines contain not only protective antigen(s) but also an adjuvant component that triggers innate immune activation… (More)
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Highly Cited
2003
Highly Cited
2003
Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans
In animals, effective immune responses against malignancies and against several infectious pathogens, including malaria, are… (More)
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Highly Cited
2000
Highly Cited
2000
Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination.
With accumulating evidence indicating the importance of cytotoxic T lymphocytes (CTLs) in containing human immunodeficiency virus… (More)
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Highly Cited
2000
Highly Cited
2000
Increased DNA vaccine delivery and immunogenicity by electroporation in vivo.
DNA vaccines have been demonstrated to be potent in small animals but are less effective in primates. One limiting factor may be… (More)
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Highly Cited
2000
Highly Cited
2000
Cationic microparticles: A potent delivery system for DNA vaccines.
An approach involving the preparation of biodegradable microparticles with a cationic surface was developed to improve the… (More)
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Highly Cited
1999
Highly Cited
1999
Comparative genomics of BCG vaccines by whole-genome DNA microarray.
Bacille Calmette-Guérin (BCG) vaccines are live attenuated strains of Mycobacterium bovis administered to prevent tuberculosis… (More)
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Highly Cited
1998
Highly Cited
1998
Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine.
CD8+ cytotoxic T lymphocytes (CTLs) are critical for protection against intracellular pathogens but often have been difficult to… (More)
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Highly Cited
1997
Highly Cited
1997
Contribution of CpG motifs to the immunogenicity of DNA vaccines.
We previously showed that bacterial DNA contains immunostimulatory motifs consisting of unmethylated CpG dinucleotides flanked by… (More)
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