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VU0364572

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Cocaine addiction is a chronic illness characterized by maladaptive drug-induced neuroplastic changes that confer lasting… Expand
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2018
2018
Alzheimer's disease (AD) is a neurodegenerative disease that disproportionately impacts memory and the hippocampus. However, it… Expand
2017
2017
Alzheimer's disease (AD) is the leading cause of dementia worldwide, and currently no disease-modifying therapy is available to… Expand
2016
2016
The muscarinic M1 acetylcholine receptor is a key target for drugs aimed at treating cognitive dysfunction, including the memory… Expand
2014
2014
Acetylcholine signaling through muscarinic receptors has been shown to benefit memory performance in some conditions, but pan… Expand
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2013
2013
Effects of selective allosteric activation of M1 and M4 muscarinic receptors on object recognition memory performance in rats By… Expand
2012
2012
We previously reported the discovery of VU0364572 and VU0357017 as M(1)-selective agonists that appear to activate M(1) through… Expand
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2011
2011
Herein we report the discovery and SAR of a novel series of M(1) agonists based on the MLPCN probe, ML071. From this, VU0364572… Expand