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VDAC1 wt Allele

Known as: VDAC-1, PORIN, Voltage-Dependent Anion Channel 1 wt Allele 
Human VDAC1 wild-type allele is located within 5q31 and is approximately 33 kb in length. This allele, which encodes voltage-dependent anion… 
National Institutes of Health

Related topics

Related topics

11 relations
ApoptosisHomo sapiensIonophore activityLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy
Introduction: Enhancement of glucose metabolism and repression of oxidative phosphorylation followed by the Warburg effect is the… 
Highly Cited
2012
Highly Cited
2012
Mediation of the Antiapoptotic Activity of Bcl-xL Protein upon Interaction with VDAC1 Protein*
Background: Bcl-xL is overexpressed in cancer, contributing to resistance to chemotherapy. Results: Bcl-xL directly interacts… 
Highly Cited
2009
Highly Cited
2009
Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase.
Review
2008
Review
2008
VDAC regulation: role of cytosolic proteins and mitochondrial lipids
It was recently asserted that the voltage-dependent anion channel (VDAC) serves as a global regulator, or governor, of… 
Review
2008
Review
2008
Uncovering the role of VDAC in the regulation of cell life and death
Proper cell activity requires an efficient exchange of molecules between mitochondria and cytoplasm. Lying in the outer… 
Highly Cited
2005
Highly Cited
2005
Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria.
The VDAC (voltage-dependent anion channel) plays a central role in apoptosis, participating in the release of apoptogenic factors… 
Highly Cited
2003
Highly Cited
2003
VDAC is a conserved element of death pathways in plant and animal systems.
Highly Cited
2000
Highly Cited
2000
Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC
Gelsolin is a Ca2+-dependent actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate… 
Highly Cited
1998
Highly Cited
1998
ATP transport through a single mitochondrial channel, VDAC, studied by current fluctuation analysis.
Highly Cited
1997
Highly Cited
1997
Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein
The permeability of the outer mitochondrial membrane to most metabolites is believed to be based in an outer membrane, channel… 
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