VAV1 protein, human

Known as: VAV1 Protein, VAV1 Gene Product, vav 1 oncogene portein, human 
VAV1 protein is a proto-oncogene product with features of a transcription factor, including an N-terminal acidic region, a proline-rich region, and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Mac-1-dependent crawling is a new step in the leukocyte recruitment cascade that follows LFA-1-dependent adhesion and precedes… (More)
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Highly Cited
2007
Highly Cited
2007
Aging-related erectile dysfunction is characterized by a loss of smooth muscle cells (SMCs) and fibrosis in the corpora cavernosa… (More)
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Review
2005
Review
2005
The Vav family proteins (Vav1, Vav2, Vav3) are cytoplasmic guanine nucleotide exchange factors (GEFs) for Rho-family GTPases. T… (More)
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Highly Cited
2005
Highly Cited
2005
Herein, we show that the hematopoietic-specific GEF VAV1 is ectopically expressed in primary pancreatic adenocarcinomas due to… (More)
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Highly Cited
2003
Highly Cited
2003
Here, we present data suggesting a novel mechanism for regulation of natural killer (NK) cell cytotoxicity through inhibitory… (More)
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Highly Cited
2003
Highly Cited
2003
The guanine nucleotide exchange factor Vav1 regulates actin polymerization and contributes to cytotoxicity by natural killer (NK… (More)
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Highly Cited
2002
Highly Cited
2002
Vav1 is a signal transducing protein required for T cell receptor (TCR) signals that drive positive and negative selection in the… (More)
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Highly Cited
2000
Highly Cited
2000
Vav proteins are guanine nucleotide exchange factors for Rho family GTPases which activate pathways leading to actin cytoskeletal… (More)
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Highly Cited
1998
Highly Cited
1998
CD19 is a coreceptor that amplifies signaling by membrane immunoglobulin (mIg) to promote responses of the B lymphocyte to T… (More)
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Highly Cited
1995
Highly Cited
1995
DURING lymphocyte development, cellular proliferation and posi-tive and negative selection events ensure the production of T and… (More)
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