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Uroplakins

Known as: Uroplakin, Uroplakins [Chemical/Ingredient] 
Specialized membrane glycoproteins that are found on UROTHELIUM cells. They associate into a hexagonal array of 16-nm cell surface particles which… 
National Institutes of Health

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Papers overview

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Review
2011
Review
2011
Immunohistochemical diagnosis of renal neoplasms.
CONTEXT Histologic diagnosis of renal neoplasm is usually straightforward by routine light microscopy. However, immunomarkers may… 
Highly Cited
2009
Highly Cited
2009
Bacteria-Induced Uroplakin Signaling Mediates Bladder Response to Infection
Urinary tract infections are the second most common infectious disease in humans and are predominantly caused by uropathogenic E… 
Highly Cited
2008
Highly Cited
2008
Abnormal expression of differentiation related proteins and proteoglycan core proteins in the urothelium of patients with interstitial cystitis.
Highly Cited
2007
Highly Cited
2007
The popcorn plaques
Imaging of inflammation in atherosclerotic lesions may identify plaques vulnerable to rupture, and lead to better assessment of… 
Highly Cited
2006
Highly Cited
2006
Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-Å resolution
Tetraspanin uroplakins (UPs) Ia and Ib, together with their single-spanning transmembrane protein partners UP II and IIIa, form a… 
Highly Cited
2004
Highly Cited
2004
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases
The apical surface of mouse urothelium is covered by two-dimensional crystals (plaques) of uroplakin (UP) particles. To study… 
Highly Cited
2001
Highly Cited
2001
Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition.
The apical surfaces of urothelial cells are almost entirely covered with plaques consisting of crystalline, hexagonal arrays of… 
Highly Cited
2000
Highly Cited
2000
Ablation of Uroplakin III Gene Results in Small Urothelial Plaques, Urothelial Leakage, and Vesicoureteral Reflux
Urothelium synthesizes a group of integral membrane proteins called uroplakins, which form two-dimensional crystals (urothelial… 
Highly Cited
1996
Highly Cited
1996
In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infections.
Urinary tract infections, caused mainly by Escherichia coli, are among the most common infectious diseases. Most isolates of the… 
Highly Cited
1994
Highly Cited
1994
Precursor sequence, processing, and urothelium-specific expression of a major 15-kDa protein subunit of asymmetric unit membrane.
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