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UniPR129

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2014-2017
0120142017

Related topics

Related topics

3 relations

Broader (2)

Lithocholic AcidTryptophan
analogs & derivatives

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
UniPR129
Tryptophan
Lithocholic Acid
analogs & derivatives

Papers overview

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2018
2018
Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction.
Eph/ephrin system is an emerging target for cancer therapy but the lack of potent, stable and orally bioavailable compounds is… (More)
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2017
2017
Metadynamics for Perspective Drug Design: Computationally Driven Synthesis of New Protein-Protein Interaction Inhibitors Targeting the EphA2 Receptor.
Metadynamics (META-D) is emerging as a powerful method for the computation of the multidimensional free-energy surface (FES… (More)
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2015
2015
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists.
The EphA2 receptor and its ephrin-A1 ligand form a key cell communication system, which has been found overexpressed in many… (More)
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2014
2014
UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations.
BACKGROUND AND PURPOSE The Eph receptor tyrosine kinases and their ephrin ligands are key players in tumorigenesis and many… (More)
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