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UniPR129

 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Lithocholic AcidTryptophan
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC min/J Mice
The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute… Expand
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2018
2018
Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction
ABSTRACT Eph/ephrin system is an emerging target for cancer therapy but the lack of potent, stable and orally bioavailable… Expand
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2017
2017
Metadynamics for Perspective Drug Design: Computationally Driven Synthesis of New Protein-Protein Interaction Inhibitors Targeting the EphA2 Receptor.
Metadynamics (META-D) is emerging as a powerful method for the computation of the multidimensional free-energy surface (FES… Expand
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2015
2015
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists
The EphA2 receptor and its ephrin-A1 ligand form a key cell communication system, which has been found overexpressed in many… Expand
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2015
2015
EPH receptor/ephrin system: in the quest for novel anti‐angiogenic therapies: Commentary on Hassan‐Mohamed et al., Br J Pharmacol 171: 5195–5208
This article is a Commentary on Hassan‐Mohamed I, Giorgio C, Incerti M, Russo S, Pala D, Pasquale EB, Zanotti I, Vicini P… Expand
2014
2014
UniPR129 is a competitive small molecule Eph‐ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations
The Eph receptor tyrosine kinases and their ephrin ligands are key players in tumorigenesis and many reports have correlated… Expand
2014
2014
Eph/ephrin sytem: In the quest of novel anti-angiogenic therapies.
 
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