Ubiquitin-mediated Proteolysis Pathway

Known as: Ubiquitin-mediated Proteolysis 
Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
02419902017

Papers overview

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2018
2018
Hypoxia can lead to solid tumor aggressiveness by driving multiple signaling pathways. Long non-coding RNAs respond to several… (More)
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2016
2016
The present study aimed to investigate the regulatory mechanisms underlying sepsis progression in patients with tumor necrosis… (More)
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Highly Cited
2011
Highly Cited
2011
We sequenced whole exomes of ten clear cell renal cell carcinomas (ccRCCs) and performed a screen of ∼1,100 genes in 88… (More)
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2008
2008
Peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator-1alpha (PGC-1alpha) is a highly regulated… (More)
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2008
2008
Peroxisome proliferator-activated receptor (PPAR ) coactivator-1 (PGC-1 ) is a highly regulated transcriptional coactivator that… (More)
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Highly Cited
2008
Highly Cited
2008
The Cdc25A phosphatase positively regulates cell-cycle transitions, is degraded by the proteosome throughout interphase and in… (More)
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Highly Cited
2003
Highly Cited
2003
The transcription factor NF-kappaB is activated by the degradation of its inhibitor IkappaBalpha, resulting in its nuclear… (More)
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Review
2003
Review
2003
Intraneuronal inclusions containing ubiquitylated filamentous protein aggregates are a common feature of many of the major human… (More)
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Highly Cited
1999
Highly Cited
1999
The human proto-oncogene c-myc encodes a highly unstable transcription factor that promotes cell proliferation. Although the… (More)
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1993
1993
Senescent cells have less free ubiquitin and more ubiquitin-protein conjugates than do young cells. The ubiquitin-protein… (More)
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