USP8 gene

Known as: USP8, Ubiquitin Specific Protease 8 Gene, SPG59 
This gene plays a role in ubiquitin-dependent proteolysis and cell proliferation.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Cushing's disease is caused by corticotroph adenomas of the pituitary. To explore the molecular mechanisms of endocrine autonomy… (More)
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2015
2015
Cushing's disease, also known as adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (PAs) that cause excess cortisol… (More)
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2014
2014
The trafficking of AMPA receptors (AMPARs) to and from synapses is crucial for synaptic plasticity. Previous work has… (More)
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2012
2012
The seven transmembrane protein Smoothened (Smo) is a critical component of the Hedgehog (Hh) signaling pathway and is regulated… (More)
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2010
2010
Reversible ubiquitination orchestrated by the opposition of ubiquitin ligases and deubiquitinating enzymes mediates endocytic… (More)
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2009
2009
The last steps of multivesicular body (MVB) formation, human immunodeficiency virus (HIV)-1 budding and cytokinesis require a… (More)
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2008
2008
During cytokinesis, the central spindle, a bundle of interdigitated anti-parallel microtubules between separating chromosomes… (More)
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Highly Cited
2007
Highly Cited
2007
The molecular mechanisms underlying epidermal growth factor (EGF) receptor tyrosine kinase down-regulation in response to growth… (More)
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Highly Cited
2006
Highly Cited
2006
Ubiquitin-specific protease 8 (USP8) hydrolyzes mono and polyubiquitylated targets such as epidermal growth factor receptors and… (More)
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Highly Cited
2004
Highly Cited
2004
Nrdp1 is a RING finger-containing E3 ubiquitin ligase that physically interacts with and regulates steady-state cellular levels… (More)
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