Skip to search formSkip to main contentSkip to account menu

USP8 gene

Known as: USP8, Ubiquitin Specific Protease 8 Gene, SPG59 
This gene plays a role in ubiquitin-dependent proteolysis and cell proliferation.
National Institutes of Health

Related topics

Related topics

6 relations
Cell ProliferationDeubiquitinationHydrolysisProteolysis

Narrower (1)

USP8 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The diagnostic value of tumor markers in bronchoalveolar lavage fluid for the peripheral pulmonary carcinoma
To investigate the value of Ubiquitin specific peptidase 8 (USP8), Chitinase 3‐like 1 (YKL40), Heat shock protein 90a (HSP90… 
2017
2017
Cytosolic deubiquitinating enzyme USP8 is endowed with a nuclear function by the mutation associated with Cushing's disease.
Review
2016
Review
2016
BACE 1 ubiquitination and degradation
β-site amyloid precursor protein cleaving enzyme (BACE1) is the rate-limiting enzyme in the production of amyloid beta (Aβ), the… 
2015
2015
Abstract 662: USP8 modulates ubiquitination of LRIG1 for Met degradation
The Met receptor tyrosine kinase is an attractive target for cancer therapy as it promotes invasive tumor growth. SAIT301 is a… 
2015
2015
Genetics: New mutations in Cushing disease identified
Pituitary adenomas from patients with Cushing disease have been shown to have somatic mutations in USP8, which encodes a… 
2010
2010
Receptor endocytosis: Frizzled joins the ubiquitin club
Wnt/β‐catenin signalling is initiated by binding of secreted Wnt ligands to Frizzled and LRP5/6/Arrow co‐receptors. A new study… 
2004
2004
Stabilization of the E 3 Ubiquitin Ligase Nrdp 1 by the Deubiquitinating Enzyme USP 8
Nrdp1 is a RING finger-containing E3 ubiquitin ligase that physically interacts with and regulates steadystate cellular levels of… 
2002
2002
A Trio of Transition Metals in Anaerobic CO2 Fixation
Certain anaerobic microorganisms can gain energy and biomass using carbon monoxide or dioxide and dihydrogen as sole sources of… 
1999
1999
Spectrum of transforming sequences detected by tumorigenicity assay in a large series of human neoplasms
We here summarize the analysis of 126 DNA samples from patients with hematopoietic neoplasias and solid tumors and from various… 
1998
1998
An oncogenic fusion product of the phosphatidylinositol 3-kinase p85β subunit and HUMORF8, a putative deubiquitinating enzyme
Peripheral blood cell DNA from a patient with a chronic myeloproliferative disorder was tested in the tumorigenicity assay. Upon… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)