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USP13 gene

Known as: USP13, ISOPEPTIDASE T3, ISOT3 
This gene is involved in promoting protein stability.
National Institutes of Health

Related topics

Related topics

7 relations
AutophagyDeubiquitinationHydrolysisProtein Degradation Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34.
Highly Cited
2018
Highly Cited
2018
Deubiquitylases USP5 and USP13 are recruited to and regulate heat-induced stress granules through their deubiquitylating activities
ABSTRACT Stress granules are transient cytoplasmic foci induced by various stresses that contain translation-stalled mRNAs and… 
Highly Cited
2017
Highly Cited
2017
USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response
BRCA1 regulates multiple cellular pathways that maintain genomic stability including cell cycle checkpoints, DNA repair, protein… 
2017
2017
Androgen receptor promotes melanoma metastasis via altering the miRNA-539-3p/USP13/MITF/AXL signals
Early studies demonstrated that male melanoma patients have worse survival than female patients, yet the detailed mechanisms for… 
Highly Cited
2016
Highly Cited
2016
Amplification of USP13 drives ovarian cancer metabolism
Dysregulated energetic metabolism has been recently identified as a hallmark of cancer. Although mutations in metabolic enzymes… 
Highly Cited
2014
Highly Cited
2014
USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation
Physiological adaptation to proteotoxic stress in the endoplasmic reticulum (ER) requires retrotranslocation of misfolded… 
Highly Cited
2013
Highly Cited
2013
Deubiquitination and stabilization of PTEN by USP13
The tumour suppressor PTEN is frequently lost in human cancers. In addition to gene mutations and deletions, recent studies have… 
2013
2013
Deubiquitination and stabilization of PTEN by USP13
Highly Cited
2011
Highly Cited
2011
Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control
The ubiquitin-recognition protein Ufd1 facilitates clearance of misfolded proteins through the endoplasmic reticulum (ER… 
2011
2011
Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin
Deubiquitination is a reverse process of cellular ubiquitination important for many biological events. Ubiquitin (Ub)-specific… 
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