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ULBP1 gene

Known as: ULBP1, MULT1, UL16-BINDING PROTEIN 1 
This gene is involved in the function of natural killer cells.
National Institutes of Health

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ULBP1 protein, human

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ULBP1 wt Allele

Papers overview

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2019
2019
The BET-bromodomain inhibitor JQ1 renders neuroblastoma cells more resistant to NK cell-mediated recognition and killing by downregulating ligands for NKG2D and DNAM-1 receptors
Low expression of ligands for NK cell-activating receptors contributes to neuroblastoma (NB) aggressiveness. Recently, we… 
2016
2016
Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity
Polyomaviruses are a diverse family of viruses which are prevalent in the human population. However, the interactions of these… 
2015
2015
Sub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis
Alpha-tochopheryl succinate (αTOS), vitamin K3 (VK3) and vitamin C (ascorbic acid, AA) were previously shown to synergistically… 
2014
2014
Microenvironment and Immunology RAE 1 Ligands for the NKG 2 D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
The immunoreceptor NKG2D originally identified in natural killer (NK) cells recognizes ligands that are upregulated on tumor… 
2011
2011
Role of NKG2D and its ligands in the anti‐infectious activity of Vγ9Vδ2 T cells against intracellular bacteria
Human Vγ9Vδ2 T cells play a crucial role in early immune response to intracellular pathogens. Their number is drastically… 
2011
2011
Cutting Edge: NKG2D-Dependent Cytotoxicity Is Controlled by Ligand Distribution in the Target Cell Membrane
Although the importance of membrane microdomains in receptor-mediated activation of lymphocytes has been established, much less… 
2010
2010
The MHC class Ib protein ULBP 1 is a nonredundant determinant of leukemia / lymphoma susceptibility to T-cell cytotoxicity
On the path to successful immunotherapy of hematopoietic tumors, T cells offer great promise because of their human leukocyte… 
Highly Cited
2007
Highly Cited
2007
Induction of NKG2D ligands on human dendritic cells by TLR ligand stimulation and RNA virus infection.
Monocyte-derived dendritic cells (mDCs) and NK cells are reciprocally activate via cytokines and cell-cell contact. Although… 
2006
2006
TGF-b and metalloproteinases differentially suppress NKG 2 D ligand surface expression on malignant glioma cells
NKG2D ligands (NKG2DL) are expressed by infected and transformed cells. They transmit danger signals to NKG2D-expressing immune… 
Highly Cited
2002
Highly Cited
2002
Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia…
PURPOSE The purpose of the study is to investigate the tolerability of interleukin 2 (IL-2) after intensive chemotherapy in… 
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