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UK 52046

Known as: UK 52046-27, UK-52,046, UK-52046 
National Institutes of Health

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1 relation

Broader (1)

abanoquil

Papers overview

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1992
1992
Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man.
1. The dose-dependency of the alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic abanoquil (UK-52,046) was… 
1991
1991
Studies with abanoquil (UK-52,046) a novel quinoline alpha 1-adrenoceptor antagonist: I. Effects on blood pressure, heart rate and pressor responsiveness in normotensive subjects.
1. Abanoquil (UK 52,046) is a novel, quinoline-derivative, alpha 1-adrenoceptor antagonist which, on the basis of animal studies… 
1991
1991
Studies with abanoquil (UK-52,046) a novel quinoline alpha 1-adrenoceptor antagonist: II. Duration of action, pharmacokinetics and concentration-effect relationships in normotensive subjects.
1. This study further examines the quinoline-derivative abanoquil with particular respect to the duration of its alpha 1… 
1991
1991
Duration of action and effect on baroreflex function of the anti‐arrhythmic α1 antagonist UK‐52,046
Abstract— The effects of acute and chronic oral administration of UK‐52,046 (25 μg kg−1) on baroreflex function and its duration… 
1990
1990
Effect of UK-52,046, an alpha 1-adrenoceptor antagonist, on baroreflex function in man.
1. In a placebo controlled study (six healthy male subjects), the effects of UK-52,046 (0.4 microgram kg-1 i.v.) and prazosin (0… 
1990
1990
UK-52,046 (a Novel α1-Adrenoceptor Antagonist) and the Role of α-Adrenoceptor Stimulation and Blockade on Atrioventricular Conduction
Summary: The effects of increasing intravenous (i.v.) doses of prazosin, phenylephrine, flecainide, and UK- 52,046 on blood… 
1990
1990
An acute study of the electrophysiological and haemodynamic effects of intravenous UK-52,046, a novel alpha 1-adrenoceptor antagonist.
The acute electrophysiological and haemodynamic effects of UK-52,046, a novel alpha 1-adrenoceptor antagonist (0.5 microgram kg-1… 
1990
1990
Haemodynamic dose-response effects of UK-52,046 in ischaemic disease with or without impaired left ventricular function.
1. The haemodynamic effects of a new cardioselective postsynaptic alpha 1-adrenoceptor antagonist UK-52,046, were evaluated in 25… 
1990
1990
UK-52,046 (a novel alpha 1-adrenoceptor antagonist) and the role of alpha-adrenoceptor stimulation and blockade on atrioventricular conduction.
The effects of increasing intravenous (i.v.) doses of prazosin, phenylephrine, flecainide, and UK-52,046 on blood pressure (BP… 
1988
1988
Effects of the myocardial‐selective α1‐adrenoceptor antagonist UK‐52046 and atenolol, alone and in combination, on experimental cardiac arrhythmias in dogs
1 Adrenaline‐induced arrhythmias in anaesthetized dogs respired with halothane were attenuated in 3 groups of 6 dogs by either UK… 
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